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Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas.
Fortin, Jerome; Tian, Ruxiao; Zarrabi, Ida; Hill, Graham; Williams, Eleanor; Sanchez-Duffhues, Gonzalo; Thorikay, Midory; Ramachandran, Parameswaran; Siddaway, Robert; Wong, Jong Fu; Wu, Annette; Apuzzo, Lorraine N; Haight, Jillian; You-Ten, Annick; Snow, Bryan E; Wakeham, Andrew; Goldhamer, David J; Schramek, Daniel; Bullock, Alex N; Dijke, Peter Ten; Hawkins, Cynthia; Mak, Tak W.
Afiliação
  • Fortin J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada. Electronic address: jerome.fortin@uhnresearch.ca.
  • Tian R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Zarrabi I; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Hill G; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Williams E; Structural Genomics Consortium, University of Oxford, Old Road Campus, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Sanchez-Duffhues G; Department of Cell and Chemical Biology and Oncode Institute, Leiden University Medical Center, P.O. Box 9600 RC, Leiden, the Netherlands.
  • Thorikay M; Department of Cell and Chemical Biology and Oncode Institute, Leiden University Medical Center, P.O. Box 9600 RC, Leiden, the Netherlands.
  • Ramachandran P; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Siddaway R; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G1X8, Canada.
  • Wong JF; Structural Genomics Consortium, University of Oxford, Old Road Campus, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Wu A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Apuzzo LN; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06268, USA.
  • Haight J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • You-Ten A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Snow BE; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Wakeham A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Goldhamer DJ; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06268, USA.
  • Schramek D; Center for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Bullock AN; Structural Genomics Consortium, University of Oxford, Old Road Campus, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Dijke PT; Department of Cell and Chemical Biology and Oncode Institute, Leiden University Medical Center, P.O. Box 9600 RC, Leiden, the Netherlands.
  • Hawkins C; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G1X8, Canada; Division of Pathology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto,
  • Mak TW; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada. Electronic address: tmak@uhnresearch.ca.
Cancer Cell ; 37(3): 308-323.e12, 2020 03 16.
Article em En | MEDLINE | ID: mdl-32142668
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Receptores de Ativinas Tipo I / Glioma / Mutação Tipo de estudo: Prognostic_studies Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Receptores de Ativinas Tipo I / Glioma / Mutação Tipo de estudo: Prognostic_studies Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article