Regulation of autophagy by inhibitory CSPG interactions with receptor PTP&#963; and its impact on plasticity and regeneration after spinal cord injury.

Tran, Amanda Phuong; Warren, Philippa Mary; Silver, Jerry

Regulation of autophagy by inhibitory CSPG interactions with receptor PTPσ and its impact on plasticity and regeneration after spinal cord injury.

Tran, Amanda Phuong; Warren, Philippa Mary; Silver, Jerry.

Afiliação

Tran AP; Seattle Children's Hospital Research Institute, Integrative Center for Brain Research, Seattle, Washington, USA.
Warren PM; King's College London, Regeneration Group, The Wolfson Centre for Age-Related Diseases, Guy's Campus, London Bridge, London, UK.
Silver J; Case Western Reserve University, School of Medicine, Department of Neurosciences, Cleveland, OH, USA. Electronic address: jxs10@case.edu.

Exp Neurol ; 328: 113276, 2020 06.

Article em En | MEDLINE | ID: mdl-32145250

Assuntos

Proteoglicanas de Sulfatos de Condroitina/metabolismo; Regeneração Nervosa/fisiologia; Plasticidade Neuronal/fisiologia; Proteínas Tirosina Fosfatases Classe 2 Semelhantes a Receptores/metabolismo; Traumatismos da Medula Espinal/metabolismo; Animais; Autofagia/fisiologia; Humanos; Traumatismos da Medula Espinal/patologia

Palavras-chave

Autophagic flux; Autophagy; Axon regeneration; Axonal dystrophy; CSPGs; Growth cone; Lysosome; Neural plasticity; Neurodegeneration; PTPσ; Spinal cord injury; Synaptogenesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteoglicanas de Sulfatos de Condroitina / Traumatismos da Medula Espinal / Proteínas Tirosina Fosfatases Classe 2 Semelhantes a Receptores / Regeneração Nervosa / Plasticidade Neuronal Limite: Animals / Humans Idioma: En Revista: Exp Neurol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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