Targeted delivery of Auristatin PE to Hep G2 cells using folate - conjugated boron nitride nanotubes.

Li, Wei; Xie, Xi; Wu, Tiantian; Yang, Huan; Peng, Yanan; Luo, Lijie; Chen, Yongjun

Li, Wei; Xie, Xi; Wu, Tiantian; Yang, Huan; Peng, Yanan; Luo, Lijie; Chen, Yongjun.

Afiliação

Li W; State Key Laboratory of Marine Resource Utilization in South China Sea, School of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Xie X; Hainan Provincial Key Laboratory for Tropical Hydrobiology and Biotechnology, College of Marine Science, Hainan University, Haikou 570228, China.
Wu T; State Key Laboratory of Marine Resource Utilization in South China Sea, School of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Yang H; State Key Laboratory of Marine Resource Utilization in South China Sea, School of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Peng Y; State Key Laboratory of Marine Resource Utilization in South China Sea, School of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Luo L; State Key Laboratory of Marine Resource Utilization in South China Sea, School of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Chen Y; State Key Laboratory of Marine Resource Utilization in South China Sea, School of Materials Science and Engineering, Hainan University, Haikou 570228, China. Electronic address: chenyj99@163.com.

Mater Sci Eng C Mater Biol Appl ; 109: 110509, 2020 Apr.

Article em En | MEDLINE | ID: mdl-32228939

Assuntos

Aminobenzoatos; Apoptose/efeitos dos fármacos; Compostos de Boro; Sistemas de Liberação de Medicamentos; Ácido Fólico; Neoplasias Hepáticas; Nanotubos/química; Oligopeptídeos; Aminobenzoatos/química; Aminobenzoatos/farmacologia; Compostos de Boro/química; Compostos de Boro/farmacologia; Ácido Fólico/química; Ácido Fólico/farmacologia; Células Hep G2; Humanos; Neoplasias Hepáticas/tratamento farmacológico; Neoplasias Hepáticas/metabolismo; Neoplasias Hepáticas/patologia; Oligopeptídeos/química; Oligopeptídeos/farmacologia

Palavras-chave

Auristatin PE; Boron nitride nanotubes; Cytotoxicity; Targeted drug delivery

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Compostos de Boro / Sistemas de Liberação de Medicamentos / Apoptose / Nanotubos / Ácido Fólico / Aminobenzoatos / Neoplasias Hepáticas Limite: Humans Idioma: En Revista: Mater Sci Eng C Mater Biol Appl Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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