The C-terminal tails of the mitochondrial transcription factors Mtf1 and TFB2M are part of an autoinhibitory mechanism that regulates DNA binding.

Basu, Urmimala; Mishra, Nandini; Farooqui, Mohammed; Shen, Jiayu; Johnson, Laura C; Patel, Smita S

Basu, Urmimala; Mishra, Nandini; Farooqui, Mohammed; Shen, Jiayu; Johnson, Laura C; Patel, Smita S.

Afiliação

Basu U; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey 08854.
Mishra N; Graduate School of Biomedical Sciences, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey 08854.
Farooqui M; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey 08854.
Shen J; Undergraduate Honors Scholars Program, School of Arts and Sciences, Rutgers University, New Brunswick, New Jersey 08901.
Johnson LC; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey 08854.
Patel SS; Undergraduate Honors Scholars Program, School of Arts and Sciences, Rutgers University, New Brunswick, New Jersey 08901.

J Biol Chem ; 295(20): 6823-6830, 2020 05 15.

Article em En | MEDLINE | ID: mdl-32241911

Assuntos

DNA Fúngico/metabolismo; DNA Mitocondrial/metabolismo; Proteínas Mitocondriais/metabolismo; Proteínas de Saccharomyces cerevisiae/metabolismo; Saccharomyces cerevisiae/metabolismo; Fatores de Transcrição/metabolismo; Transcrição Gênica; DNA Fúngico/genética; DNA Mitocondrial/genética; RNA Polimerases Dirigidas por DNA/genética; RNA Polimerases Dirigidas por DNA/metabolismo; Proteínas Mitocondriais/genética; Domínios Proteicos; Saccharomyces cerevisiae/genética; Proteínas de Saccharomyces cerevisiae/genética; Fatores de Transcrição/genética

Palavras-chave

Mtf1; RNA polymerase; TFB2M; autoinhibition; fluorescence anisotropy; mitochondria; mitochondrial RNA polymerase; mitochondrial transcription factors; proteinDNA interaction; transcriptional coactivator

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Fatores de Transcrição / Transcrição Gênica / DNA Fúngico / DNA Mitocondrial / Proteínas de Saccharomyces cerevisiae / Proteínas Mitocondriais Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article

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