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Multiple analyte profiling (MAP) index as a powerful diagnostic and therapeutic monitoring tool.
Elsabahy, Mahmoud; Wooley, Karen L; Hendricksen, Amy; Oh, Kenneth.
Afiliação
  • Elsabahy M; Departments of Chemistry, Chemical Engineering, and Materials Science and Engineering, and Laboratory for Synthetic-Biologic Interactions, Texas A&M University, College Station, TX 77842, USA; Science Academy, Badr University in Cairo (BUC), Badr City, Cairo, Egypt; Department of Pharmaceutics,
  • Wooley KL; Departments of Chemistry, Chemical Engineering, and Materials Science and Engineering, and Laboratory for Synthetic-Biologic Interactions, Texas A&M University, College Station, TX 77842, USA. Electronic address: wooley@chem.tamu.edu.
  • Hendricksen A; Bio-Rad Laboratories, Hercules, CA 94547, USA.
  • Oh K; Bio-Rad Laboratories, Hercules, CA 94547, USA.
Methods ; 190: 26-32, 2021 06.
Article em En | MEDLINE | ID: mdl-32243921
A robust data mining algorithm is presented as a critical solution to the challenge of managing intensive data generated from the recently developed multiplexing techniques, which allow simultaneous detection of up to 500 biomarkers in a few microliters of a single sample. Furthermore, detailed methodology is provided for exploiting the new algorithm along with examples for description of the first application as a powerful diagnostic and therapeutic monitoring tool in the management of breast cancer, as a disease model.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais Tipo de estudo: Diagnostic_studies Idioma: En Revista: Methods Assunto da revista: BIOQUIMICA Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais Tipo de estudo: Diagnostic_studies Idioma: En Revista: Methods Assunto da revista: BIOQUIMICA Ano de publicação: 2021 Tipo de documento: Article