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Stavudine exposure results in developmental abnormalities by causing DNA damage, inhibiting cell proliferation and inducing apoptosis in mouse embryos.
Ao, Rui-Fang; Liang, Yu-Xiang; Liu, Xiao-Qing; Tan, Kui; Wang, Xiaoling; Liu, Dan; Zhang, Ting; Sun, Gongqin; Xie, Jun.
Afiliação
  • Ao RF; Department of Biochemistry and Molecular Biology, Shanxi Key Laboratory of Birth Defect and Cell Regeneration, Shanxi Medical University, Taiyuan 030001, Shanxi, China.
  • Liang YX; Department of Biochemistry and Molecular Biology, Shanxi Key Laboratory of Birth Defect and Cell Regeneration, Shanxi Medical University, Taiyuan 030001, Shanxi, China.
  • Liu XQ; Department of Biochemistry and Molecular Biology, Shanxi Key Laboratory of Birth Defect and Cell Regeneration, Shanxi Medical University, Taiyuan 030001, Shanxi, China.
  • Tan K; Department of Biochemistry and Molecular Biology, Shanxi Key Laboratory of Birth Defect and Cell Regeneration, Shanxi Medical University, Taiyuan 030001, Shanxi, China.
  • Wang X; Department of Biochemistry and Molecular Biology, Shanxi Key Laboratory of Birth Defect and Cell Regeneration, Shanxi Medical University, Taiyuan 030001, Shanxi, China.
  • Liu D; Department of Biochemistry and Molecular Biology, Shanxi Key Laboratory of Birth Defect and Cell Regeneration, Shanxi Medical University, Taiyuan 030001, Shanxi, China.
  • Zhang T; Capital Institute of Pediatrics, Beijing 100020, China. Electronic address: Zhangtingcv@126.com.
  • Sun G; Department of Cell & Molecular Biology, University of Rhode Island, 389 CBLS Building, 120 Flagg Road, Kingston, RI, 02881, USA.
  • Xie J; Department of Biochemistry and Molecular Biology, Shanxi Key Laboratory of Birth Defect and Cell Regeneration, Shanxi Medical University, Taiyuan 030001, Shanxi, China. Electronic address: junxie@sxmu.edu.cn.
Toxicology ; 439: 152443, 2020 06.
Article em En | MEDLINE | ID: mdl-32278789
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anormalidades Induzidas por Medicamentos / Apoptose / Estavudina / Fármacos Anti-HIV Limite: Animals / Pregnancy Idioma: En Revista: Toxicology Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anormalidades Induzidas por Medicamentos / Apoptose / Estavudina / Fármacos Anti-HIV Limite: Animals / Pregnancy Idioma: En Revista: Toxicology Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China