Polymorphism of the alpha-1-fucosyltransferase (FUT1) gene in several wild boar (Sus scrofa) populations in France and link to edema disease.
Res Vet Sci
; 131: 78-86, 2020 Aug.
Article
em En
| MEDLINE
| ID: mdl-32311589
ABSTRACT
BACKGROUND:
In 2013, an outbreak of edema disease in a population of wild boars (Sus scrofa) took place. This was the first described case as reported worldwide. An enterotoxigenic Escherichia coli (presenting the Stx2e and F18 virulence factors) is the main pathogen for this disease in wild boar. The alpha-1-fucosyltransferase gene (FUT1) has been identified as the gene regulating the expression of the receptor for E. coli stx2e F18 bacteria in domestic pigs affected by the disease. The genotypic frequencies of the FUT1 gene in European wild boars have not yet been investigated. The genotypes of wild boars for this gene were determined in four French departments with or without edema diseases cases.RESULTS:
All of the wild boars analyzed had a genotype susceptible to the disease (GG or AG). The recessive, resistant A allele was found for the first time in wild boars, but in a very small proportion of individuals (7/222). No statistical differences were found between healthy hunted wild boars versus wild boars found dead by edema disease or among the four French departments.CONCLUSIONS:
These results suggest that further mortality due to edema disease remains possible in wild boars in France.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Doenças dos Suínos
/
Edema
/
Infecções por Escherichia coli
/
Escherichia coli Enterotoxigênica
/
Fucosiltransferases
Tipo de estudo:
Prognostic_studies
Limite:
Animals
País/Região como assunto:
Europa
Idioma:
En
Revista:
Res Vet Sci
Ano de publicação:
2020
Tipo de documento:
Article