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Application of magnetic nanoparticles in nucleic acid detection.
Tang, Congli; He, Ziyu; Liu, Hongmei; Xu, Yuyue; Huang, Hao; Yang, Gaojian; Xiao, Ziqi; Li, Song; Liu, Hongna; Deng, Yan; Chen, Zhu; Chen, Hui; He, Nongyue.
Afiliação
  • Tang C; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China.
  • He Z; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China.
  • Liu H; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China.
  • Xu Y; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China.
  • Huang H; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China.
  • Yang G; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China.
  • Xiao Z; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China.
  • Li S; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China. sosong1980@gmail.com.
  • Liu H; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China.
  • Deng Y; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China.
  • Chen Z; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, 210096, China.
  • Chen H; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China.
  • He N; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, 412007, China.
J Nanobiotechnology ; 18(1): 62, 2020 Apr 21.
Article em En | MEDLINE | ID: mdl-32316985
ABSTRACT
Nucleic acid is the main material for storing, copying, and transmitting genetic information. Gene sequencing is of great significance in DNA damage research, gene therapy, mutation analysis, bacterial infection, drug development, and clinical diagnosis. Gene detection has a wide range of applications, such as environmental, biomedical, pharmaceutical, agriculture and forensic medicine to name a few. Compared with Sanger sequencing, high-throughput sequencing technology has the advantages of larger output, high resolution, and low cost which greatly promotes the application of sequencing technology in life science research. Magnetic nanoparticles, as an important part of nanomaterials, have been widely used in various applications because of their good dispersion, high surface area, low cost, easy separation in buffer systems and signal detection. Based on the above, the application of magnetic nanoparticles in nucleic acid detection was reviewed.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Nucleicos / Nanopartículas de Magnetita Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: J Nanobiotechnology Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Nucleicos / Nanopartículas de Magnetita Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: J Nanobiotechnology Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China