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Selective targeting of PI3Kδ suppresses human IL-17-producing T cells and innate-like lymphocytes and may be therapeutic for IL-17-mediated diseases.
Chen, Sijia; Paveley, Ross; Kraal, Lianne; Sritharan, Lathees; Stevens, Elizabeth; Dedi, Neesha; Shock, Anthony; Shaw, Stevan; Juarez, Maria; Yeremenko, Nataliya; Baeten, Dominique; Payne, Andrew.
Afiliação
  • Chen S; Department of Clinical Immunology and Rheumatology, Amsterdam Rheumatology & immunology Center (ARC), Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, the Netherlands; Department of Experimental Immunology, Infection and Immunity Institute, Amsterd
  • Paveley R; UCB Pharma, Slough, UK.
  • Kraal L; Department of Clinical Immunology and Rheumatology, Amsterdam Rheumatology & immunology Center (ARC), Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, the Netherlands; Department of Experimental Immunology, Infection and Immunity Institute, Amsterd
  • Sritharan L; Department of Clinical Immunology and Rheumatology, Amsterdam Rheumatology & immunology Center (ARC), Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, the Netherlands; Department of Experimental Immunology, Infection and Immunity Institute, Amsterd
  • Stevens E; UCB Pharma, Slough, UK.
  • Dedi N; UCB Pharma, Slough, UK.
  • Shock A; UCB Pharma, Slough, UK.
  • Shaw S; UCB Pharma, Slough, UK.
  • Juarez M; UCB Pharma, Slough, UK.
  • Yeremenko N; Department of Clinical Immunology and Rheumatology, Amsterdam Rheumatology & immunology Center (ARC), Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, the Netherlands; Department of Experimental Immunology, Infection and Immunity Institute, Amsterd
  • Baeten D; Department of Clinical Immunology and Rheumatology, Amsterdam Rheumatology & immunology Center (ARC), Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, the Netherlands; UCB Pharma, Slough, UK.
  • Payne A; UCB Pharma, Slough, UK.
J Autoimmun ; 111: 102435, 2020 07.
Article em En | MEDLINE | ID: mdl-32360069
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psoríase / Piridinas / Quinolinas / Espondilite Anquilosante / Linfócitos / Células Th17 / Classe I de Fosfatidilinositol 3-Quinases / Fibroblastos / Sinoviócitos / Anti-Inflamatórios Limite: Female / Humans / Male / Middle aged Idioma: En Revista: J Autoimmun Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psoríase / Piridinas / Quinolinas / Espondilite Anquilosante / Linfócitos / Células Th17 / Classe I de Fosfatidilinositol 3-Quinases / Fibroblastos / Sinoviócitos / Anti-Inflamatórios Limite: Female / Humans / Male / Middle aged Idioma: En Revista: J Autoimmun Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2020 Tipo de documento: Article