Your browser doesn't support javascript.
loading
[Performance of the FIB-4 index in esophageal varices screening in patients with the diagnosis of liver cirrhosis]. / Desempeñ o del índice FIB-4 en el despistaje de vá rices esofá gicas en pacientes con el diagnóstico de cirrosis hepá tica.
Cá Lamo-Guzmá N, Bernardo; De Vinatea-Serrano, Luis; Piscoya, Alejandro; Segura, Eddy R.
Afiliação
  • Cá Lamo-Guzmá N B; Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas. Lima, Perú.
  • De Vinatea-Serrano L; Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas. Lima, Perú.
  • Piscoya A; Servicio de Gastroenterología, Complejo Hospitalario Guillermo Kaelin de la Fuente, EsSalud. Lima, Perú; Unidad de Revisiones Sistemá ticas y Meta-aná lisis, Guías de Prá ctica Clínica y Evaluaciones de Tecnologías Sanitarias, Universidad San Ignacio de Loyola. Lima, Perú.
  • Segura ER; Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas. Lima, Perú; Division of Infectious Diseases, Department of Medicine, University of California. Los Angeles, CA, USA.
Rev Gastroenterol Peru ; 40(1): 29-35, 2020.
Article em Es | MEDLINE | ID: mdl-32369463
INTRODUCTION: The diagnosis of esophageal varices in cirrhotic patients is made by the upper gastrointestinal endoscopy. Multiple non-invasive predictors have been studied for the diag-nosis of esophageal varices. The objective of this study is to testthe FIB4 index as screening of esophageal varices in patients with liver cirrhosis. MATERIALS AND METHODS: A cross-sectional analytic study was developed in four national hospital using hepatic cirrhosis patient's medi-cal files. We assessed the information using univariate and bivariate analysis, sensitivity, speci-ficity, predictive positive and negative value, the positive and negative likelihood ratio calcu-lation of the esophageal varices screening and its size. We built ROC curve for every analysis group. RESULTS: The study included 289 liver cirrhosis patients. Most of the patients were male (54.33%). 77.85% patients had esophageal varices. The distribution of varices was 19.03%, 35.99% and 22.84% for large, medium and small varices, respectively. In the FIB-4 index analysis for the presence of varices, it was found a sensitivity of 81.3%, specificity of 37.5% (AUC: 0.57). The calculation for variceal size showed a sensitivity of 81.8%, specificity of 23.9% (AUC: 0.50). In the analysis of FIB-4 index for prophylaxis groups was found a sensitivity of 81.8% and a specificity of 28.5% (AUC: 0.54). CONCLUSIONS: The FIB-4 index has no good performance in the screening for the presence of esophageal varices and its size in liver cirrhosis patients.
Assuntos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Gravidade de Doença / Varizes Esofágicas e Gástricas / Regras de Decisão Clínica / Cirrose Hepática Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: Es Revista: Rev Gastroenterol Peru Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2020 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Gravidade de Doença / Varizes Esofágicas e Gástricas / Regras de Decisão Clínica / Cirrose Hepática Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: Es Revista: Rev Gastroenterol Peru Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2020 Tipo de documento: Article