Development and validation of the self-reported disability status scale (SRDSS) to estimate EDSS-categories.
Mult Scler Relat Disord
; 42: 102148, 2020 Jul.
Article
em En
| MEDLINE
| ID: mdl-32371376
ABSTRACT
BACKGROUND:
Clinician-assessed Expanded Disease Status Scale (EDSS) is gold standard in clinical investigations but normally unavailable in population-based, patient-centred MS-studies. Our objective was to develop a self-reported gait measure reflecting EDSS-categories.METHODS:
We developed the self-reported disability status scale (SRDSS) with three categories (≤3.5, 4-6.5, ≥7) based on three mobility-related questions. The SRDSS was determined for 173 persons with MS and validated against clinical EDSS to calculate sensitivity and specificity.RESULTS:
Accuracy was 88.4% (153 correctly classified) and weighted kappa 0.73 (0.62-0.84). Sensitivity/specificity-pairs were 94.5%/77.8%, 69.0%/94.7% and 100%/98.2% for SRDSS ≤3.5, 4-6.5 and ≥7, respectively.CONCLUSIONS:
Self-reported SRDSS approximates EDSS-categories well and fosters comparability between clinical and population-based studies.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psicometria
/
Índice de Gravidade de Doença
/
Autorrelato
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Marcha
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Esclerose Múltipla
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Adult
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Mult Scler Relat Disord
Ano de publicação:
2020
Tipo de documento:
Article