Red nucleus IL-6 mediates the maintenance of neuropathic pain by inducing the productions of TNF-&#945; and IL-1ß through the JAK2/STAT3 and ERK signaling pathways.

Yang, Qing-Qing; Li, Hao-Nan; Zhang, Shu-Ting; Yu, Yan-Li; Wei, Wei; Zhang, Xi; Wang, Jun-Yang; Zeng, Xiao-Yan

Red nucleus IL-6 mediates the maintenance of neuropathic pain by inducing the productions of TNF-α and IL-1ß through the JAK2/STAT3 and ERK signaling pathways.

Yang, Qing-Qing; Li, Hao-Nan; Zhang, Shu-Ting; Yu, Yan-Li; Wei, Wei; Zhang, Xi; Wang, Jun-Yang; Zeng, Xiao-Yan.

Afiliação

Yang QQ; Department of Laboratory Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Li HN; Department of Pathogenic Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Zhang ST; Department of Pathogenic Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yu YL; Department of Pathogenic Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Wei W; Department of Pathogenic Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Zhang X; Department of Pathogenic Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Wang JY; Department of Pathogenic Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Zeng XY; Department of Pathogenic Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.

Neuropathology ; 40(4): 347-357, 2020 Aug.

Article em En | MEDLINE | ID: mdl-32380573

Assuntos

Interleucina-6/metabolismo; Neuralgia/metabolismo; Núcleo Rubro/metabolismo; Animais; Hiperalgesia/metabolismo; Interleucina-1beta/metabolismo; Janus Quinase 2/metabolismo; Sistema de Sinalização das MAP Quinases/fisiologia; Masculino; Neuralgia/etiologia; Traumatismos dos Nervos Periféricos/complicações; Traumatismos dos Nervos Periféricos/metabolismo; Ratos; Ratos Sprague-Dawley; Fator de Transcrição STAT3/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

interleukin-1ß; interleukin-6; neuropathic pain; red nucleus; tumor necrosis factor-α

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Núcleo Rubro / Interleucina-6 / Neuralgia Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Neuropathology Assunto da revista: NEUROLOGIA / PATOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google