Rule-in thresholds for DELFIA Xpress PlGF 1-2-3 test for suspected pre-eclampsia.
Pregnancy Hypertens
; 21: 35-37, 2020 Jul.
Article
em En
| MEDLINE
| ID: mdl-32388118
ABSTRACT
We aimed to establish a rule-in threshold for the DELFIA Xpress placental growth factor (PlGF) 1-2-3 test. Plasma EDTA samples from 305 women presenting with suspected pre-eclampsia before 35 weeks' gestation were analysed using three different PlGF-based tests PlGF 1-2-3 test (Perkin Elmer); Triage PlGF test (Quidel); Elecsys immunoassay sFlt-1/PlGF ratio (Roche). The rule-in threshold for PlGF 1-2-3 test created with equivalent specificity of the Quidel and Roche tests was 50 pg/ml. This can be used as a rule-in test for diagnosis of preterm pre-eclampsiarequiring delivery within 14 days (specificity 95.0% (95% CI 91.7-97.2%), positive predictive value50 (95% CI 30.6-69.4%), positive likelihood ratio 10.7 (5.8-20).
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pré-Eclâmpsia
/
Fator de Crescimento Placentário
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
Limite:
Female
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Humans
/
Pregnancy
Idioma:
En
Revista:
Pregnancy Hypertens
Ano de publicação:
2020
Tipo de documento:
Article