ß-arrestin 2 quenches TLR signaling to facilitate the immune evasion of EPEC.

Chen, Zijuan; Zhou, Ruixue; Zhang, Yihua; Hao, Doudou; Wang, Yu; Huang, Shichao; Liu, Ningning; Xia, Chunmei; Yissachar, Nissan; Huang, Feng; Chu, Yiwei; Yan, Dapeng

Chen, Zijuan; Zhou, Ruixue; Zhang, Yihua; Hao, Doudou; Wang, Yu; Huang, Shichao; Liu, Ningning; Xia, Chunmei; Yissachar, Nissan; Huang, Feng; Chu, Yiwei; Yan, Dapeng.

Afiliação

Chen Z; Department of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.
Zhou R; Department of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.
Zhang Y; Department of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.
Hao D; Department of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.
Wang Y; Department of Microbiology and Biochemical Pharmacy, National Engineering Research Centre of Immunological Products, College of Pharmacy, Third Military Medical University , Chongqing, China.
Huang S; Shanghai Key Laboratory of Signaling and Disease Research, Laboratory of Receptor-based Bio-medicine, the Collaborative Innovation Center for Brain Science, School of Life Sciences and Technology, Tongji University , Shanghai, China.
Liu N; School of Public Health, Shanghai Jiao Tong University School of Medicine , Shanghai, China.
Xia C; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University , Shanghai, China.
Yissachar N; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University , Ramat-Gan, Israel.
Huang F; Beijing Hospital of Traditional Chinese Medicine, Capital Medical University , Beijing, China.
Chu Y; Department of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.
Yan D; Department of Immunology, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University , Shanghai, China.

Gut Microbes ; 11(5): 1423-1437, 2020 09 02.

Article em En | MEDLINE | ID: mdl-32403971

Assuntos

Escherichia coli Enteropatogênica/patogenicidade; Evasão da Resposta Imune; Macrófagos/microbiologia; Receptores Toll-Like/metabolismo; beta-Arrestina 2/metabolismo; Motivos de Aminoácidos; Animais; Células Cultivadas; Citocinas/genética; Citocinas/metabolismo; Escherichia coli Enteropatogênica/imunologia; Escherichia coli Enteropatogênica/metabolismo; Proteínas de Escherichia coli/química; Proteínas de Escherichia coli/metabolismo; Células HEK293; Células HeLa; Humanos; MAP Quinase Quinase Quinases/metabolismo; Macrófagos Peritoneais/microbiologia; Camundongos; Camundongos Endogâmicos C57BL; Fosforilação; Ligação Proteica; Proteína Tirosina Fosfatase não Receptora Tipo 6/metabolismo; Células RAW 264.7; RNA Interferente Pequeno; Receptores de Superfície Celular/química; Receptores de Superfície Celular/metabolismo; Transdução de Sinais; Fator 6 Associado a Receptor de TNF/genética; Fator 6 Associado a Receptor de TNF/metabolismo; beta-Arrestina 2/genética

Palavras-chave

EPEC; TAK1; TLR signaling; TRAF6; immune evasion; ß-arrestin 2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Toll-Like / Escherichia coli Enteropatogênica / Evasão da Resposta Imune / Beta-Arrestina 2 / Macrófagos Limite: Animals / Humans Idioma: En Revista: Gut Microbes Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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