Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells.

Chennakrishnaiah, Shilpa; Tsering, Thupten; Gregory, Caroline; Tawil, Nadim; Spinelli, Cristiana; Montermini, Laura; Karatzas, Nicolaos; Aprikian, Saro; Choi, Dongsic; Klewes, Ludger; Mai, Sabine; Rak, Janusz

Chennakrishnaiah, Shilpa; Tsering, Thupten; Gregory, Caroline; Tawil, Nadim; Spinelli, Cristiana; Montermini, Laura; Karatzas, Nicolaos; Aprikian, Saro; Choi, Dongsic; Klewes, Ludger; Mai, Sabine; Rak, Janusz.

Afiliação

Chennakrishnaiah S; Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, H4A 3J1, Canada.
Tsering T; Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, H4A 3J1, Canada.
Gregory C; Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, H4A 3J1, Canada.
Tawil N; Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, H4A 3J1, Canada.
Spinelli C; Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, H4A 3J1, Canada.
Montermini L; Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, H4A 3J1, Canada.
Karatzas N; Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, H4A 3J1, Canada.
Aprikian S; Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, H4A 3J1, Canada.
Choi D; Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, H4A 3J1, Canada.
Klewes L; Department of Cell Biology, Research Institute of Oncology and Hematology, Cancer Care Manitoba, University of Manitoba, Winnipeg, Canada.
Mai S; Department of Cell Biology, Research Institute of Oncology and Hematology, Cancer Care Manitoba, University of Manitoba, Winnipeg, Canada.
Rak J; Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, H4A 3J1, Canada. janusz.rak@mcgill.ca.

Sci Rep ; 10(1): 8532, 2020 05 22.

Article em En | MEDLINE | ID: mdl-32444772

Assuntos

Transformação Celular Neoplásica/patologia; Células Endoteliais/patologia; Vesículas Extracelulares/patologia; Glioblastoma/patologia; Micronúcleos com Defeito Cromossômico; Mutação; Proteínas Proto-Oncogênicas p21(ras)/genética; Proliferação de Células; Transformação Celular Neoplásica/genética; Transformação Celular Neoplásica/metabolismo; Células Endoteliais/metabolismo; Vesículas Extracelulares/genética; Vesículas Extracelulares/metabolismo; Glioblastoma/genética; Glioblastoma/metabolismo; Humanos; Proteoma; Células Tumorais Cultivadas

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transformação Celular Neoplásica / Proteínas Proto-Oncogênicas p21(ras) / Glioblastoma / Células Endoteliais / Micronúcleos com Defeito Cromossômico / Vesículas Extracelulares / Mutação Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá

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