New-onset depression among children, adolescents, and adults with hidradenitis suppurativa.
J Am Acad Dermatol
; 83(5): 1360-1366, 2020 Nov.
Article
em En
| MEDLINE
| ID: mdl-32446831
ABSTRACT
BACKGROUND:
Information on the risk of depression among children, adolescents, and adults with hidradenitis suppurativa (HS) is limited.OBJECTIVE:
To compare the risk of new-onset depression in patients with HS with that of control individuals.METHODS:
Retrospective cohort analysis of 49,280 adult and 3042 pediatric patients with HS and matched control individuals identified by using electronic health record data. The primary outcome was incident depression.RESULTS:
The crude incidence rate was 4.8 per 100 person-years in adult patients with HS compared to 3.0 per 100 person-years in control individuals. Among pediatric patients, the crude incidence rate was 4.2 per 100 person-years in patients with HS compared with 2.3 per 100 person-years in control individuals. In adjusted analysis, adults and pediatric patients with HS had a 10% (hazard ratio, 1.10; 95% confidence interval, 1.07-1.13; P < .001) and 26% (hazard ratio, 1.26; 95% confidence interval, 1.10-1.44; P < .001), respectively, increased risk of developing depression compared to control individuals. Among patients with HS, factors associated with depression included female sex, white race, smoking, and body mass index/obesity in adults and pediatric patients and substance abuse in adults only.LIMITATIONS:
Patients not seeking care in health systems within the database were not captured.CONCLUSION:
Children, adolescents, and adults with HS are at an increased risk for developing depression, independent of other common risk factors for depression.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hidradenite Supurativa
/
Depressão
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Child
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Am Acad Dermatol
Ano de publicação:
2020
Tipo de documento:
Article