[Antinuclear antibodies in the diagnostics of rheumatic diseases]. / Antinukleäre Antikörper in der Diagnostik rheumatischer Erkrankungen.
Z Rheumatol
; 79(5): 447-458, 2020 Jun.
Article
em De
| MEDLINE
| ID: mdl-32458159
ABSTRACT
Testing for antinuclear antibodies (ANA) on human epithelial cell lines (HEp-2) using indirect immunofluorescence (IIF) is central for ruling out or for diagnosing connective tissue diseases and other diseases, such as primary biliary cholangitis and autoimmune hepatitis as well as drug-induced ANA. The comprehensive description of 29 different ANA-IIF patterns by the international consensus of ANA patterns (ICAP) facilitates the harmonization of ANA-IIF diagnostics. Positive ANA tests are frequently observed in healthy individuals and a reason for referral to rheumatologists. In these cases, the detection of anti-DFS70 antibodies can be helpful to exclude systemic autoimmune rheumatic diseases.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Anticorpos Antinucleares
/
Doenças Reumáticas
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
De
Revista:
Z Rheumatol
Ano de publicação:
2020
Tipo de documento:
Article