BMP9 exhibits dual and coupled roles in inducing osteogenic and angiogenic differentiation of mesenchymal stem cells.

Xiao, Haozhuo; Wang, Xiaoyu; Wang, Claire; Dai, Guangming; Zhu, Zhenglin; Gao, Shengqiang; He, Baicheng; Liao, Junyi; Huang, Wei

Xiao, Haozhuo; Wang, Xiaoyu; Wang, Claire; Dai, Guangming; Zhu, Zhenglin; Gao, Shengqiang; He, Baicheng; Liao, Junyi; Huang, Wei.

Afiliação

Xiao H; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Wang X; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Wang C; Department of Computational and Applied Mathematics, Rice University, Houston, TX 77005, U.S.A.
Dai G; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Zhu Z; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Gao S; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
He B; Key Laboratory for Biochemistry and Molecular Pharmacology of Chongqing, Chongqing Medical University, Chongqing 400016, China.
Liao J; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Huang W; Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.

Biosci Rep ; 40(6)2020 06 26.

Article em En | MEDLINE | ID: mdl-32478395

Assuntos

Diferenciação Celular; Fator 2 de Diferenciação de Crescimento/metabolismo; Células-Tronco Mesenquimais/metabolismo; Neovascularização Fisiológica; Osteogênese; Animais; Regulação da Expressão Gênica; Fator 2 de Diferenciação de Crescimento/genética; Células HEK293; Humanos; Transplante de Células-Tronco Mesenquimais; Camundongos; Camundongos Nus; Molécula-1 de Adesão Celular Endotelial a Plaquetas/genética; Molécula-1 de Adesão Celular Endotelial a Plaquetas/metabolismo; Transdução de Sinais; Fator A de Crescimento do Endotélio Vascular/genética; Fator A de Crescimento do Endotélio Vascular/metabolismo

Palavras-chave

Angiogenic differentiation; BMP9; MSCs; Osteogenesis-angiogenesis coupling; Osteogenic differentiation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteogênese / Diferenciação Celular / Neovascularização Fisiológica / Fator 2 de Diferenciação de Crescimento / Células-Tronco Mesenquimais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Biosci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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