Improving Proteoform Identifications in Complex Systems Through Integration of Bottom-Up and Top-Down Data.

Schaffer, Leah V; Millikin, Robert J; Shortreed, Michael R; Scalf, Mark; Smith, Lloyd M

Schaffer, Leah V; Millikin, Robert J; Shortreed, Michael R; Scalf, Mark; Smith, Lloyd M.

Afiliação

Schaffer LV; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Millikin RJ; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Shortreed MR; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Scalf M; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Smith LM; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.

J Proteome Res ; 19(8): 3510-3517, 2020 08 07.

Article em En | MEDLINE | ID: mdl-32584579

Assuntos

Proteômica; Espectrometria de Massas em Tandem; Humanos; Processamento de Proteína Pós-Traducional; Proteoma/metabolismo; Software

Palavras-chave

bottom-up proteomics; post-translational modification; protein inference; proteoforms; software; top-down proteomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteômica / Espectrometria de Massas em Tandem Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: J Proteome Res Assunto da revista: BIOQUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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