Your browser doesn't support javascript.
loading
Measurement of the ratio of cerebral oxygen consumption to glucose utilization by positron emission tomography: its consistency with the values determined by the Kety-Schmidt method in normal volunteers.
Hatazawa, J; Ito, M; Matsuzawa, T; Ido, T; Watanuki, S.
Afiliação
  • Hatazawa J; Division of Nuclear Medicine, Tohoku University, Sendai, Japan.
J Cereb Blood Flow Metab ; 8(3): 426-32, 1988 Jun.
Article em En | MEDLINE | ID: mdl-3259242
The regional interrelationship between cerebral oxygen consumption (CMRO2) and cerebral glucose utilization (CMRGlc) was studied in normal subjects using positron emission tomography (PET) and the 15O steady-state inhalation and the [18F]fluoro deoxyglucose method. The use of standard sets of rate constants and the model lumped constant of 0.52 as well as the regional blood-brain partition coefficient for water and the blood volume correction for oxygen extraction fraction provided a CMRO2/CMRGlc ratio of 4.89 in the cortical gray matter, 5.27 in the basal ganglia and 5.82 in the centrum semiovale (white matter). The values of CMRO2/CMRGlc for the basal ganglia and the white matter were consistent with those reported for the whole brain with the Kety-Schmidt method. There was no significant difference in the CMRO2/CMRGlc between the basal ganglia and the white matter indicating the similar nature of in vivo oxidative metabolism of glucose in neuron-rich region and glial cell-rich region.
Assuntos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Consumo de Oxigênio / Encéfalo / Tomografia Computadorizada de Emissão / Glucose Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Cereb Blood Flow Metab Ano de publicação: 1988 Tipo de documento: Article País de afiliação: Japão
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Consumo de Oxigênio / Encéfalo / Tomografia Computadorizada de Emissão / Glucose Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Cereb Blood Flow Metab Ano de publicação: 1988 Tipo de documento: Article País de afiliação: Japão