Identifying epigenetic biomarkers of established prognostic factors and survival in a clinical cohort of individuals with oropharyngeal cancer.

Langdon, Ryan; Richmond, Rebecca; Elliott, Hannah R; Dudding, Tom; Kazmi, Nabila; Penfold, Chris; Ingarfield, Kate; Ho, Karen; Bretherick, Andrew; Haley, Chris; Zeng, Yanni; Walker, Rosie M; Pawlita, Michael; Waterboer, Tim; Gaunt, Tom; Smith, George Davey; Suderman, Matthew; Thomas, Steve; Ness, Andy; Relton, Caroline

Langdon, Ryan; Richmond, Rebecca; Elliott, Hannah R; Dudding, Tom; Kazmi, Nabila; Penfold, Chris; Ingarfield, Kate; Ho, Karen; Bretherick, Andrew; Haley, Chris; Zeng, Yanni; Walker, Rosie M; Pawlita, Michael; Waterboer, Tim; Gaunt, Tom; Smith, George Davey; Suderman, Matthew; Thomas, Steve; Ness, Andy; Relton, Caroline.

Afiliação

Langdon R; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK. ryan.langdon@bristol.ac.uk.
Richmond R; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. ryan.langdon@bristol.ac.uk.
Elliott HR; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK. rebecca.richmond@bristol.ac.uk.
Dudding T; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. rebecca.richmond@bristol.ac.uk.
Kazmi N; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Penfold C; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Ingarfield K; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Ho K; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Bretherick A; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Haley C; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Zeng Y; NIHR Bristol Biomedical Research Centre, University Hospitals Bristol and University of Bristol, Bristol, UK.
Walker RM; NIHR Bristol Biomedical Research Centre, University Hospitals Bristol and University of Bristol, Bristol, UK.
Pawlita M; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Waterboer T; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Gaunt T; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Scotland, Bristol, EH4 2XU, UK.
Smith GD; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Scotland, Bristol, EH4 2XU, UK.
Suderman M; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Scotland, Bristol, EH4 2XU, UK.
Thomas S; Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Ness A; Guangdong Province Translational Forensic Medicine Engineering Technology Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Relton C; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

Clin Epigenetics ; 12(1): 95, 2020 06 29.

Article em En | MEDLINE | ID: mdl-32600451

Assuntos

Biomarcadores/análise; Epigênese Genética/genética; Epigenômica/métodos; Neoplasias Orofaríngeas/genética; Adulto; Consumo de Bebidas Alcoólicas/efeitos adversos; Consumo de Bebidas Alcoólicas/genética; Estudos de Casos e Controles; Estudos de Coortes; Ilhas de CpG/genética; Metilação de DNA; Epigenoma/genética; Feminino; Humanos; Masculino; Análise da Randomização Mendeliana/métodos; Pessoa de Meia-Idade; Proteínas Musculares/genética; Proteínas Oncogênicas Virais/sangue; Neoplasias Orofaríngeas/etiologia; Neoplasias Orofaríngeas/mortalidade; Neoplasias Orofaríngeas/virologia; Infecções por Papillomavirus/complicações; Infecções por Papillomavirus/genética; Prognóstico; Proteínas Serina-Treonina Quinases/genética; Proteínas/genética; Proteínas Repressoras/sangue; Fatores de Risco; Fumar/efeitos adversos; Fumar/genética; Taxa de Sobrevida

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores / Neoplasias Orofaríngeas / Epigênese Genética / Epigenômica Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Epigenetics Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido

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