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Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study.
Forgetta, Vincenzo; Keller-Baruch, Julyan; Forest, Marie; Durand, Audrey; Bhatnagar, Sahir; Kemp, John P; Nethander, Maria; Evans, Daniel; Morris, John A; Kiel, Douglas P; Rivadeneira, Fernando; Johansson, Helena; Harvey, Nicholas C; Mellström, Dan; Karlsson, Magnus; Cooper, Cyrus; Evans, David M; Clarke, Robert; Kanis, John A; Orwoll, Eric; McCloskey, Eugene V; Ohlsson, Claes; Pineau, Joelle; Leslie, William D; Greenwood, Celia M T; Richards, J Brent.
Afiliação
  • Forgetta V; Centre for Clinical Epidemiology, Department of Medicine, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Québec, Canada.
  • Keller-Baruch J; Department of Human Genetics, McGill University, Montréal, Québec, Canada.
  • Forest M; Centre for Clinical Epidemiology, Department of Medicine, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Québec, Canada.
  • Durand A; School of Computer Science, McGill University, Montréal, Québec, Canada.
  • Bhatnagar S; Centre for Clinical Epidemiology, Department of Medicine, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Québec, Canada.
  • Kemp JP; University of Queensland Diamantina Institute, University of Queensland, Woolloongabba, Queensland, Australia.
  • Nethander M; Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Evans D; Bioinformatics Core Facility, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Morris JA; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute for Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Kiel DP; California Pacific Medical Center Research Institute, San Francisco, California, United States of America.
  • Rivadeneira F; Centre for Clinical Epidemiology, Department of Medicine, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Québec, Canada.
  • Johansson H; Institute for Aging Research, Hebrew SeniorLife, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Broad Institute of MIT & Harvard University, Boston, Massachusetts, United States of America.
  • Harvey NC; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands.
  • Mellström D; Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, United Kingdom.
  • Karlsson M; Australian Catholic University, Melbourne, Victoria, Australia.
  • Cooper C; Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom.
  • Evans DM; National Institute for Health Research Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.
  • Clarke R; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute for Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Kanis JA; Department of Orthopaedics and Clinical Sciences, Lund University, Skane University Hospital, Malmö, Sweden.
  • Orwoll E; Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom.
  • McCloskey EV; National Institute for Health Research Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.
  • Ohlsson C; National Institute for Health Research Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.
  • Pineau J; University of Queensland Diamantina Institute, University of Queensland, Woolloongabba, Queensland, Australia.
  • Leslie WD; Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Greenwood CMT; Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, United Kingdom.
  • Richards JB; Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, United Kingdom.
PLoS Med ; 17(7): e1003152, 2020 07.
Article em En | MEDLINE | ID: mdl-32614825
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Programas de Rastreamento / Medição de Risco / Herança Multifatorial / Fraturas por Osteoporose Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: PLoS Med Assunto da revista: MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Programas de Rastreamento / Medição de Risco / Herança Multifatorial / Fraturas por Osteoporose Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: PLoS Med Assunto da revista: MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá