Development of nimesulide amorphous solid dispersions via supercritical anti-solvent process for dissolution enhancement.

Liu, Guijin; Gong, Ling; Zhang, Jiawen; Wu, Zhenyao; Deng, Han; Deng, Shiming

Liu, Guijin; Gong, Ling; Zhang, Jiawen; Wu, Zhenyao; Deng, Han; Deng, Shiming.

Afiliação

Liu G; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Life and Pharmaceutical Sciences, Hainan University, Haikou, China. Electronic address: liugj@hainanu.edu.cn.
Gong L; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Life and Pharmaceutical Sciences, Hainan University, Haikou, China.
Zhang J; Honz Pharmaceutical Co., Ltd., Haikou, China.
Wu Z; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Life and Pharmaceutical Sciences, Hainan University, Haikou, China.
Deng H; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Life and Pharmaceutical Sciences, Hainan University, Haikou, China.
Deng S; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Life and Pharmaceutical Sciences, Hainan University, Haikou, China.

Eur J Pharm Sci ; 152: 105457, 2020 Sep 01.

Article em En | MEDLINE | ID: mdl-32645426

Assuntos

Povidona; Liberação Controlada de Fármacos; Reprodutibilidade dos Testes; Solubilidade; Solventes; Sulfonamidas

Palavras-chave

Amorphous solid dispersions; Dissolution; Nimesulide; Stability; Supercritical fluid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Povidona Tipo de estudo: Prognostic_studies Idioma: En Revista: Eur J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article

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