Scalp hair whorl patterns in patients affected by Neurofibromatosis Type 1: A case-control study.
Int J Trichology
; 12(2): 56-61, 2020.
Article
em En
| MEDLINE
| ID: mdl-32684676
ABSTRACT
BACKGROUND:
The hair whorl denotes the spiral disposition of hairs around an axis, which is determined by the follicle growing direction. Atypical variants of scalp hair patterns, identified by abnormally placed or multiple whorls, have been associated with early brain developmental disorders and several dysmorphic syndromes. MATERIALS ANDMETHODS:
A 6-month case-control, prospective monocentric study included an overall number of 557 children. A logistic regression analysis was performed to evaluate the relationship between localization, the number of scalp hair whorls, and their association with neurofibromatosis type 1 (NF1).RESULTS:
NF1 positively correlates with a frontal localization, whereas a negative association was found with a parietal whorl pattern (P < 0.001).CONCLUSION:
Evaluation of scalp whorls gains importance in the neonatal settings and may contribute to suspect the early diagnosis of NF1, as the related National Institutes of Health diagnostic criteria cannot be usually observed at an early age.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Idioma:
En
Revista:
Int J Trichology
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Itália