Expression of GPR55 and either cannabinoid CB<sub>1</sub> or CB<sub>2</sub> heteroreceptor complexes in the caudate, putamen, and accumbens nuclei of control, parkinsonian, and dyskinetic non-human primates.

Martínez-Pinilla, Eva; Rico, Alberto J; Rivas-Santisteban, Rafael; Lillo, Jaume; Roda, Elvira; Navarro, Gemma; Lanciego, José Luis; Franco, Rafael

Expression of GPR55 and either cannabinoid CB₁ or CB₂ heteroreceptor complexes in the caudate, putamen, and accumbens nuclei of control, parkinsonian, and dyskinetic non-human primates.

Martínez-Pinilla, Eva; Rico, Alberto J; Rivas-Santisteban, Rafael; Lillo, Jaume; Roda, Elvira; Navarro, Gemma; Lanciego, José Luis; Franco, Rafael.

Afiliação

Martínez-Pinilla E; Department of Morphology and Cell Biology, Faculty of Medicine, University of Oviedo, Julián Clavería s/n, 33006, Asturias, Spain. martinezpinillaeva@gmail.com.
Rico AJ; Instituto de Neurociencias del Principado de Asturias (INEUROPA), Asturias, Spain. martinezpinillaeva@gmail.com.
Rivas-Santisteban R; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Asturias, Spain. martinezpinillaeva@gmail.com.
Lillo J; Neurosciences Division, Centre for Applied Medical Research, CIMA, University of Navarra, Avenida Pío XII, 55, 31008, Pamplona, Spain.
Roda E; Instituto de Investigaciones Sanitarias de Navarra (IdiSNA), Pamplona, Spain.
Navarro G; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Lanciego JL; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Franco R; Molecular Neurobiology Laboratory, Department of Biochemistry and Molecular Biomedicine, School of Chemistry, Universitat de Barcelona, Diagonal 643, 08028, Barcelona, Spain.

Brain Struct Funct ; 225(7): 2153-2164, 2020 Sep.

Article em En | MEDLINE | ID: mdl-32691218

Assuntos

Núcleo Caudado/metabolismo; Discinesias/metabolismo; Núcleo Accumbens/metabolismo; Transtornos Parkinsonianos/metabolismo; Putamen/metabolismo; Receptores de Canabinoides/metabolismo; Animais; Modelos Animais de Doenças; Macaca fascicularis; Masculino; Receptor CB1 de Canabinoide/metabolismo; Receptor CB2 de Canabinoide/metabolismo

Palavras-chave

G-protein coupled receptor (GPCR) heteromer; Levodopa; Parkinson's disease; Proximity ligation assay (PLA); Striatum

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Putamen / Núcleo Caudado / Transtornos Parkinsonianos / Discinesias / Receptores de Canabinoides / Núcleo Accumbens Limite: Animals Idioma: En Revista: Brain Struct Funct Assunto da revista: CEREBRO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Espanha

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