Translation Initiation Site Profiling Reveals Widespread Synthesis of Non-AUG-Initiated Protein Isoforms in Yeast.

Eisenberg, Amy R; Higdon, Andrea L; Hollerer, Ina; Fields, Alexander P; Jungreis, Irwin; Diamond, Paige D; Kellis, Manolis; Jovanovic, Marko; Brar, Gloria A

Eisenberg, Amy R; Higdon, Andrea L; Hollerer, Ina; Fields, Alexander P; Jungreis, Irwin; Diamond, Paige D; Kellis, Manolis; Jovanovic, Marko; Brar, Gloria A.

Afiliação

Eisenberg AR; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Higdon AL; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Center for Computational Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Hollerer I; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Fields AP; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA.
Jungreis I; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Diamond PD; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Kellis M; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Jovanovic M; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
Brar GA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Center for Computational Biology, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: gabrar@berkeley.edu.

Cell Syst ; 11(2): 145-160.e5, 2020 08 26.

Article em En | MEDLINE | ID: mdl-32710835

Assuntos

Códon/metabolismo; Iniciação Traducional da Cadeia Peptídica/genética; Biossíntese de Proteínas/genética; Isoformas de Proteínas/metabolismo; Saccharomyces cerevisiae/genética

Palavras-chave

alternate protein isoforms; codon; gene expression; genome annotation; meiosis; near-cognate; ribosome profiling; translation; translation initiation site; yeast

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Iniciação Traducional da Cadeia Peptídica / Saccharomyces cerevisiae / Biossíntese de Proteínas / Códon / Isoformas de Proteínas Tipo de estudo: Prognostic_studies Idioma: En Revista: Cell Syst Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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