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Current Insights in Cutaneous Lupus Erythematosus Immunopathogenesis.
Garelli, Colton J; Refat, Maggi Ahmed; Nanaware, Padma P; Ramirez-Ortiz, Zaida G; Rashighi, Mehdi; Richmond, Jillian M.
Afiliação
  • Garelli CJ; Department of Dermatology, University of Massachusetts Medical School, Worcester, MA, United States.
  • Refat MA; Department of Dermatology, University of Massachusetts Medical School, Worcester, MA, United States.
  • Nanaware PP; Department of Pathology, University of Massachusetts Medical School, Worcester, MA, United States.
  • Ramirez-Ortiz ZG; Department of Medicine, University of Massachusetts Medical School, Worcester, MA, United States.
  • Rashighi M; Department of Dermatology, University of Massachusetts Medical School, Worcester, MA, United States.
  • Richmond JM; Department of Dermatology, University of Massachusetts Medical School, Worcester, MA, United States.
Front Immunol ; 11: 1353, 2020.
Article em En | MEDLINE | ID: mdl-32714331
ABSTRACT
Cutaneous Lupus Erythematosus (CLE) is a clinically diverse group of autoimmune skin diseases with shared histological features of interface dermatitis and autoantibodies deposited at the dermal-epidermal junction. Various genetic and environmental triggers of CLE promote infiltration of T cells, B cells, neutrophils, antigen presenting cells, and NK cells into lesional skin. In this mini-review, we will discuss the clinical features of CLE, insights into CLE immunopathogenesis, and novel treatment approaches.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lúpus Eritematoso Cutâneo Limite: Humans Idioma: En Revista: Front Immunol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lúpus Eritematoso Cutâneo Limite: Humans Idioma: En Revista: Front Immunol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos