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Inhibition of DDR1 enhances in vivo chemosensitivity in KRAS-mutant lung adenocarcinoma.
Nokin, Marie-Julie; Darbo, Elodie; Travert, Camille; Drogat, Benjamin; Lacouture, Aurélie; San José, Sonia; Cabrera, Nuria; Turcq, Béatrice; Prouzet-Mauleon, Valérie; Falcone, Mattia; Villanueva, Alberto; Wang, Haiyun; Herfs, Michael; Mosteiro, Miguel; Jänne, Pasi A; Pujol, Jean-Louis; Maraver, Antonio; Barbacid, Mariano; Nadal, Ernest; Santamaría, David; Ambrogio, Chiara.
Afiliação
  • Nokin MJ; University of Bordeaux, INSERM U1218, ACTION Laboratory, IECB, Pessac, France.
  • Darbo E; University of Bordeaux, INSERM U1218, ACTION Laboratory, Bordeaux INP, CNRS, LaBRI, UMR5800, Talence, France.
  • Travert C; Institut de Recherche en Cancérologie de Montpellier (IRCM), Université de Montpellier, Institut Régional du Cancer de Montpellier (ICM), Montpellier, France.
  • Drogat B; University of Bordeaux, INSERM U1218, ACTION Laboratory, IECB, Pessac, France.
  • Lacouture A; University of Bordeaux, INSERM U1218, ACTION Laboratory, IECB, Pessac, France.
  • San José S; University of Bordeaux, INSERM U1218, ACTION Laboratory, IECB, Pessac, France.
  • Cabrera N; Molecular Oncology Program, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.
  • Turcq B; University of Bordeaux, INSERM U1218, ACTION Laboratory, Laboratory of Mammary and Leukaemic Oncogenesis, Bordeaux, France.
  • Prouzet-Mauleon V; University of Bordeaux, INSERM U1218, ACTION Laboratory, Laboratory of Mammary and Leukaemic Oncogenesis, Bordeaux, France.
  • Falcone M; Molecular Oncology Program, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.
  • Villanueva A; Translational Research Laboratory, Catalan Institute of Oncology, IDIBELL, L'Hospitalet, Barcelona, Spain.
  • Wang H; School of Life Science and Technology, Tongji University, Shanghai, China.
  • Herfs M; Laboratory of Experimental Pathology, GIGA-Cancer, University of Liège, Liège, Belgium.
  • Mosteiro M; Department of Medical Oncology, Catalan Institute of Oncology, Clinical Research in Solid Tumors (CReST) Group, Oncobell Program, IDIBELL, L'Hospitalet, Barcelona, Spain.
  • Jänne PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Pujol JL; Institut de Recherche en Cancérologie de Montpellier (IRCM), Université de Montpellier, Institut Régional du Cancer de Montpellier (ICM), Montpellier, France.
  • Maraver A; Montpellier Academic Hospital, Hôpital Arnaud de Villeneuve, Montpellier, France.
  • Barbacid M; Institut de Recherche en Cancérologie de Montpellier (IRCM), Université de Montpellier, Institut Régional du Cancer de Montpellier (ICM), Montpellier, France.
  • Nadal E; Molecular Oncology Program, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.
  • Santamaría D; Department of Medical Oncology, Catalan Institute of Oncology, Clinical Research in Solid Tumors (CReST) Group, Oncobell Program, IDIBELL, L'Hospitalet, Barcelona, Spain.
  • Ambrogio C; University of Bordeaux, INSERM U1218, ACTION Laboratory, IECB, Pessac, France.
JCI Insight ; 5(15)2020 08 06.
Article em En | MEDLINE | ID: mdl-32759499
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogênicas p21(ras) / Resistencia a Medicamentos Antineoplásicos / Receptor com Domínio Discoidina 1 / Adenocarcinoma de Pulmão / Neoplasias Pulmonares / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: JCI Insight Ano de publicação: 2020 Tipo de documento: Article País de afiliação: França
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogênicas p21(ras) / Resistencia a Medicamentos Antineoplásicos / Receptor com Domínio Discoidina 1 / Adenocarcinoma de Pulmão / Neoplasias Pulmonares / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: JCI Insight Ano de publicação: 2020 Tipo de documento: Article País de afiliação: França