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The accelerator-based boron neutron capture reaction evaluation system for head and neck cancer.
Wang, Shou; Igawa, Kazuyo; Ogawara, Ryo; Suda, Mitsuru; Hamano, Tsuyoshi; Ibaragi, Soichiro; Hanafusa, Tadashi; Ichikawa, Yasuaki; Sasaki, Akira.
Afiliação
  • Wang S; Department of Oral and Maxillofacial Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata Kita-ku Okayama, 700-855, Japan.
  • Igawa K; Neutron Therapy Research Center, Okayama University, 2-5-1 Shikata Kita-ku Okayama, 700-855, Japan. Electronic address: igawakazuyo@okayama-u.ac.jp.
  • Ogawara R; Advanced Research Center for Beam Science, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan; National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.
  • Suda M; National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.
  • Hamano T; National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.
  • Ibaragi S; Department of Oral and Maxillofacial Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata Kita-ku Okayama, 700-855, Japan.
  • Hanafusa T; Neutron Therapy Research Center, Okayama University, 2-5-1 Shikata Kita-ku Okayama, 700-855, Japan.
  • Ichikawa Y; Neutron Therapy Research Center, Okayama University, 2-5-1 Shikata Kita-ku Okayama, 700-855, Japan.
  • Sasaki A; Department of Oral and Maxillofacial Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata Kita-ku Okayama, 700-855, Japan.
Appl Radiat Isot ; 165: 109271, 2020 Nov.
Article em En | MEDLINE | ID: mdl-32771869
ABSTRACT
The purpose of this study is to assess accelerator-based boron neutron capture reaction (BNCR) in human tumor cell lines by colony formation assay and modified high density survival assay (HDS assay). The results of post irradiation survival rate in human oral squamous cell carcinoma and osteosarcoma using both assays were similar. Therefore, HDS assay would be efficient to evaluate BNCR in not only tumor cells but also in normal cells as BNCT screening.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aceleradores de Partículas / Carcinoma de Células Escamosas / Osteossarcoma / Terapia por Captura de Nêutron de Boro / Neoplasias de Cabeça e Pescoço Limite: Humans Idioma: En Revista: Appl Radiat Isot Assunto da revista: MEDICINA NUCLEAR / SAUDE AMBIENTAL Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aceleradores de Partículas / Carcinoma de Células Escamosas / Osteossarcoma / Terapia por Captura de Nêutron de Boro / Neoplasias de Cabeça e Pescoço Limite: Humans Idioma: En Revista: Appl Radiat Isot Assunto da revista: MEDICINA NUCLEAR / SAUDE AMBIENTAL Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão