Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue.

Bayram, Jan; Malcova, Ivana; Sinkovec, Larisa; Holubova, Jana; Streparola, Gaia; Jurnecka, David; Kucera, Jan; Sedlacek, Radislav; Sebo, Peter; Kamanova, Jana

Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue.

Bayram, Jan; Malcova, Ivana; Sinkovec, Larisa; Holubova, Jana; Streparola, Gaia; Jurnecka, David; Kucera, Jan; Sedlacek, Radislav; Sebo, Peter; Kamanova, Jana.

Afiliação

Bayram J; Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.
Malcova I; Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.
Sinkovec L; Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.
Holubova J; Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.
Streparola G; Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic.
Jurnecka D; Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.
Kucera J; Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic.
Sedlacek R; Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic.
Sebo P; Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.
Kamanova J; Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.

PLoS Pathog ; 16(8): e1008512, 2020 08.

Article em En | MEDLINE | ID: mdl-32776984

Assuntos

Alanina/metabolismo; Proteínas de Bactérias/metabolismo; Bordetella pertussis/fisiologia; Regulação Bacteriana da Expressão Gênica; Coqueluche/patologia; Alanina/genética; Animais; Proteínas de Bactérias/genética; Feminino; Células HeLa; Humanos; Camundongos; Camundongos Endogâmicos BALB C; Mutação; Sistemas de Secreção Tipo III/genética; Sistemas de Secreção Tipo III/metabolismo; Virulência; Coqueluche/genética; Coqueluche/microbiologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Bordetella pertussis / Regulação Bacteriana da Expressão Gênica / Coqueluche / Alanina Limite: Animals / Female / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2020 Tipo de documento: Article País de afiliação: República Tcheca

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