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Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aß Self-Aggregation and Metal Chelation-Induced Aß Aggregation.
Bowroju, Suresh K; Mainali, Nirjal; Ayyadevara, Srinivas; Penthala, Narsimha R; Krishnamachari, Sesha; Kakraba, Samuel; Reis, Robert J Shmookler; Crooks, Peter A.
Afiliação
  • Bowroju SK; Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Mainali N; Bioinformatics Program, University of Arkansas at Little Rock and University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Ayyadevara S; Central Arkansas Veterans Healthcare Service, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Penthala NR; Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Krishnamachari S; Central Arkansas Veterans Healthcare Service, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Kakraba S; Bioinformatics Program, University of Arkansas at Little Rock and University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Reis RJS; Bioinformatics Program, University of Arkansas at Little Rock and University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Crooks PA; Central Arkansas Veterans Healthcare Service, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Molecules ; 25(16)2020 Aug 08.
Article em En | MEDLINE | ID: mdl-32784464
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Desenho de Fármacos / Quelantes / Peptídeos beta-Amiloides / Oxiquinolina / Agregados Proteicos / Indóis Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Desenho de Fármacos / Quelantes / Peptídeos beta-Amiloides / Oxiquinolina / Agregados Proteicos / Indóis Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos