Nuclear receptor phosphorylation in xenobiotic signal transduction.

Negishi, Masahiko; Kobayashi, Kaoru; Sakuma, Tsutomu; Sueyoshi, Tatsuya

Negishi, Masahiko; Kobayashi, Kaoru; Sakuma, Tsutomu; Sueyoshi, Tatsuya.

Afiliação

Negishi M; Pharmacogenetics Section, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA. Electronic address: negishi@niehs.nih.gov.
Kobayashi K; Department of Biopharmaceutics, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan.
Sakuma T; School of Pharmaceutical Sciences, Ohu University, Koriyama, Fukushima, Japan.
Sueyoshi T; Pharmacogenetics Section, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.

J Biol Chem ; 295(45): 15210-15225, 2020 11 06.

Article em En | MEDLINE | ID: mdl-32788213

Assuntos

Receptores Citoplasmáticos e Nucleares/metabolismo; Transdução de Sinais; Xenobióticos/metabolismo; Animais; Sistema Enzimático do Citocromo P-450/genética; Sistema Enzimático do Citocromo P-450/metabolismo; Fosforilação

Palavras-chave

CAR; Nuclear receptors; PXR; cell signaling; drug metabolism; estrogen; gene regulation; induction; nuclear receptor; phenobarbital; phosphorylation; steroid hormone receptors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Xenobióticos / Receptores Citoplasmáticos e Nucleares Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article

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