Association Between Sleep Apnea Risk Score and Retinal Microvasculature Using Optical Coherence Tomography Angiography.
Am J Ophthalmol
; 221: 55-64, 2021 01.
Article
em En
| MEDLINE
| ID: mdl-32882221
ABSTRACT
PURPOSE:
To investigate the retinal vessel changes at peripapillary and parafoveal regions using optical coherence tomography angiography in patients with varying obstructive sleep apnea syndrome (OSAS) risk, identified by the STOP-BANG questionnaire.DESIGN:
Prospective, hospital-based cross-sectional study.METHODS:
Participants were divided into 3 groups based on the OSAS risk score. Flow areas and vessel densities were calculated at peripapillary and parafoveal regions using optical coherence tomography angiography. Microvasculature changes between the 3 groups and correlation between OSAS risk score and vascular changes were calculated.RESULTS:
Six hundred and six eyes of 303 patients were included in groups 1 (n = 96), 2 (n = 135), and 3 (n = 72). In patients with high OSAS risk, an increase in flow areas (P = .011) and vessel densities (P = .002) in superficial capillary plexus was noted. In contrast, flow areas (P = .003) and vessel densities (P < .000) in deep capillary plexus were reduced. Positive correlation was noted between sleep scores and vessel densities in superficial capillary plexus (P = .04). Negative correlation was noted between sleep scores and flow areas (P = .003) and vessel densities (P ≤ .001) in deep capillary plexus.CONCLUSION:
The sleep apnea questionnaire is an easy method of identifying the disease severity stage, but polysomnography still remains the definitive gold standard. Optical coherence tomography angiography shows some associations with disease severity, but it cannot be used unambiguously to distinguish the severity of sleep apnea.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Disco Óptico
/
Vasos Retinianos
/
Angiofluoresceinografia
/
Apneia Obstrutiva do Sono
/
Tomografia de Coerência Óptica
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Am J Ophthalmol
Ano de publicação:
2021
Tipo de documento:
Article