Proteomic Profiling Reveals Roles of Stress Response, Ca<sup>2+</sup> Transient Dysregulation, and Novel Signaling Pathways in Alcohol-Induced Cardiotoxicity.

Liu, Rui; Sun, Fangxu; Forghani, Parvin; Armand, Lawrence C; Rampoldi, Antonio; Li, Dong; Wu, Ronghu; Xu, Chunhui

Proteomic Profiling Reveals Roles of Stress Response, Ca²⁺ Transient Dysregulation, and Novel Signaling Pathways in Alcohol-Induced Cardiotoxicity.

Liu, Rui; Sun, Fangxu; Forghani, Parvin; Armand, Lawrence C; Rampoldi, Antonio; Li, Dong; Wu, Ronghu; Xu, Chunhui.

Afiliação

Liu R; From the, Department of Pediatrics, (RL, PF, LCA, AR, DL, CX), Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
Sun F; Department of Pediatrics, (RL), the Third Xiangya Hospital of Central South University, Changsha, China.
Forghani P; School of Chemistry and Biochemistry and the Petit Institute for Bioengineering and Bioscience, (FS, RW), Georgia Institute of Technology, Atlanta, Georgia.
Armand LC; From the, Department of Pediatrics, (RL, PF, LCA, AR, DL, CX), Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
Rampoldi A; From the, Department of Pediatrics, (RL, PF, LCA, AR, DL, CX), Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
Li D; From the, Department of Pediatrics, (RL, PF, LCA, AR, DL, CX), Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
Wu R; From the, Department of Pediatrics, (RL, PF, LCA, AR, DL, CX), Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
Xu C; School of Chemistry and Biochemistry and the Petit Institute for Bioengineering and Bioscience, (FS, RW), Georgia Institute of Technology, Atlanta, Georgia.

Alcohol Clin Exp Res ; 44(11): 2187-2199, 2020 11.

Article em En | MEDLINE | ID: mdl-32981093

Assuntos

Cálcio/metabolismo; Cardiotoxicidade/metabolismo; Etanol/efeitos adversos; Proteômica; Transdução de Sinais/efeitos dos fármacos; Diferenciação Celular/efeitos dos fármacos; Cromatografia Gasosa-Espectrometria de Massas; Humanos; Células-Tronco Pluripotentes Induzidas/efeitos dos fármacos; Células-Tronco Pluripotentes Induzidas/metabolismo; Miócitos Cardíacos/efeitos dos fármacos; Miócitos Cardíacos/metabolismo; Proteômica/métodos; Estresse Fisiológico/efeitos dos fármacos

Palavras-chave

Cardiomyocytes; Cardiotoxicity; EtOH; Quantitative Proteomics; Stem Cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Cálcio / Proteômica / Etanol / Cardiotoxicidade Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Alcohol Clin Exp Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Geórgia

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