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Could threshold cycle value correctly reflect the severity of novel coronavirus disease 2019 (COVID-19)?
Asai, Nobuhiro; Sakanashi, Daisuke; Ohashi, Wataru; Nakamura, Akiko; Yamada, Atsuko; Kawamoto, Yuzuka; Miyazaki, Narimi; Ohno, Tomoko; Koita, Isao; Suematsu, Hiroyuki; Kishino, Takaaki; Kato, Hideo; Hagihara, Mao; Shiota, Arufumi; Koizumi, Yusuke; Yamagishi, Yuka; Mikamo, Hiroshige.
Afiliação
  • Asai N; Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Aichi, Japan; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Sakanashi D; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Ohashi W; Division of Biostatistics, Clinical Research Center, Aichi Medical University Hospital, Japan.
  • Nakamura A; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Yamada A; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Kawamoto Y; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Miyazaki N; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Ohno T; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Koita I; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Suematsu H; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Kishino T; Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Aichi, Japan; Department of Emergency and Critical Care Medicine, Aichi Medical University Hospital, Japan.
  • Kato H; Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Aichi, Japan; University of Queensland Centre for Clinical Research, The University of Queensland, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia.
  • Hagihara M; Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Aichi, Japan; Department of Molecular Epidemiology and Biomedical Sciences, Aichi Medical University, Aichi, Japan.
  • Shiota A; Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Aichi, Japan; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Koizumi Y; Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Aichi, Japan; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Yamagishi Y; Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Aichi, Japan; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan.
  • Mikamo H; Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Aichi, Japan; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan. Electronic address: mikamo@aichi-med-u.ac.jp.
J Infect Chemother ; 27(1): 117-119, 2021 Jan.
Article em En | MEDLINE | ID: mdl-32994136
The novel coronavirus disease 2019 (COVID-19) is diagnosed by positive result of reverse transcription polymerase chain reaction (RT-PCR) for the novel coronavirus. We concluded that cycle threshold value (Ct-value) of real-time RT-PCR (rRT-PCR) assay could decrease as patients recover. Results of rRT-PCR assay could remain positive among asymptomatic patients for longer than 2 weeks. The discharge criteria of COVID-19 patients using a negative result of rRT-PCR should be reconsidered.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Reação em Cadeia da Polimerase Via Transcriptase Reversa Tipo de estudo: Diagnostic_studies Limite: Adolescent / Adult / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Infect Chemother Assunto da revista: MICROBIOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Reação em Cadeia da Polimerase Via Transcriptase Reversa Tipo de estudo: Diagnostic_studies Limite: Adolescent / Adult / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Infect Chemother Assunto da revista: MICROBIOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão