Reduced brain fractalkine-CX3CR1 signaling is involved in the impaired cognition of streptozotocin-treated mice.

Kawamura, Namiko; Katsuura, Goro; Yamada-Goto, Nobuko; Novianti, Ela; Inui, Akio; Asakawa, Akihiro

Kawamura, Namiko; Katsuura, Goro; Yamada-Goto, Nobuko; Novianti, Ela; Inui, Akio; Asakawa, Akihiro.

Afiliação

Kawamura N; Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Katsuura G; Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Yamada-Goto N; Health Center, Keio University, Japan.
Novianti E; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University, School of Medicine, Japan.
Inui A; Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Asakawa A; Pharmacological Department of Herbal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

IBRO Rep ; 9: 233-240, 2020 Dec.

Article em En | MEDLINE | ID: mdl-32995659

Palavras-chave

AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CNS, central nervous system; CX3CR1; CX3CR1, CX3C chemokine receptor 1; DEX, dexamethasone; DM, diabetes mellitus; DMSO, dimethyl sulfoxide; Diabetes; EDTA, ethylenediaminetetraacetic acid; Fractalkine; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; IGF-1, insulin-like growth factor-1; LTP, long-term potentiation; Memory; Mice; NMDA, N-methyl-d-aspartate; PPP, picropodophyllin; STZ, streptozotocin; Streptozotocin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: IBRO Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão

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