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Mechanoactivation of NOX2-generated ROS elicits persistent TRPM8 Ca2+ signals that are inhibited by oncogenic KRas.
Pratt, Stephen J P; Lee, Rachel M; Chang, Katarina T; Hernández-Ochoa, Erick O; Annis, David A; Ory, Eleanor C; Thompson, Keyata N; Bailey, Patrick C; Mathias, Trevor J; Ju, Julia A; Vitolo, Michele I; Schneider, Martin F; Stains, Joseph P; Ward, Christopher W; Martin, Stuart S.
Afiliação
  • Pratt SJP; Program in Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, MD 21201; sjppratt@umaryland.edu ssmartin@som.umaryland.edu.
  • Lee RM; Department of Pharmacology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Chang KT; Department of Physiology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Hernández-Ochoa EO; Marlene and Stewart Greenebaum National Cancer Institute Comprehensive Cancer Center, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Annis DA; Department of Pharmacology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Ory EC; Department of Physiology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Thompson KN; Marlene and Stewart Greenebaum National Cancer Institute Comprehensive Cancer Center, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Bailey PC; Department of Pharmacology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Mathias TJ; Department of Physiology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Ju JA; Marlene and Stewart Greenebaum National Cancer Institute Comprehensive Cancer Center, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Vitolo MI; Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Schneider MF; Department of Pharmacology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Stains JP; Marlene and Stewart Greenebaum National Cancer Institute Comprehensive Cancer Center, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Ward CW; Department of Pharmacology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Martin SS; Department of Physiology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Proc Natl Acad Sci U S A ; 117(42): 26008-26019, 2020 10 20.
Article em En | MEDLINE | ID: mdl-33020304
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mama / Cálcio / Proteínas Proto-Oncogênicas p21(ras) / Espécies Reativas de Oxigênio / Mecanotransdução Celular / Canais de Cátion TRPM / NADPH Oxidase 2 Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mama / Cálcio / Proteínas Proto-Oncogênicas p21(ras) / Espécies Reativas de Oxigênio / Mecanotransdução Celular / Canais de Cátion TRPM / NADPH Oxidase 2 Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article