Your browser doesn't support javascript.
loading
Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study.
Burn, Edward; You, Seng Chan; Sena, Anthony G; Kostka, Kristin; Abedtash, Hamed; Abrahão, Maria Tereza F; Alberga, Amanda; Alghoul, Heba; Alser, Osaid; Alshammari, Thamir M; Aragon, Maria; Areia, Carlos; Banda, Juan M; Cho, Jaehyeong; Culhane, Aedin C; Davydov, Alexander; DeFalco, Frank J; Duarte-Salles, Talita; DuVall, Scott; Falconer, Thomas; Fernandez-Bertolin, Sergio; Gao, Weihua; Golozar, Asieh; Hardin, Jill; Hripcsak, George; Huser, Vojtech; Jeon, Hokyun; Jing, Yonghua; Jung, Chi Young; Kaas-Hansen, Benjamin Skov; Kaduk, Denys; Kent, Seamus; Kim, Yeesuk; Kolovos, Spyros; Lane, Jennifer C E; Lee, Hyejin; Lynch, Kristine E; Makadia, Rupa; Matheny, Michael E; Mehta, Paras P; Morales, Daniel R; Natarajan, Karthik; Nyberg, Fredrik; Ostropolets, Anna; Park, Rae Woong; Park, Jimyung; Posada, Jose D; Prats-Uribe, Albert; Rao, Gowtham; Reich, Christian.
Afiliação
  • Burn E; Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.
  • You SC; Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.
  • Sena AG; Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.
  • Kostka K; Janssen Research and Development, Titusville, NJ, USA.
  • Abedtash H; Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Abrahão MTF; Real World Solutions, IQVIA, Cambridge, MA, USA.
  • Alberga A; Eli Lilly and Company, Indianapolis, IN, USA.
  • Alghoul H; Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
  • Alser O; Observational Health Data Sciences and Informatics Network, Alberta, Canada.
  • Alshammari TM; Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine.
  • Aragon M; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Areia C; Medication Safety Research Chair, King Saud University, Riyadh, Saudi Arabia.
  • Banda JM; Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.
  • Cho J; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
  • Culhane AC; Department of Computer Science, Georgia State University, Atlanta, GA, USA.
  • Davydov A; Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.
  • DeFalco FJ; Data Science, Dana-Farber Cancer Institute. Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA.
  • Duarte-Salles T; Odysseus Data Services, Inc., Cambridge, MA, USA.
  • DuVall S; Department for Microbiology, Virology and Immunology, Belarusian State Medical University, Minsk, Belarus.
  • Falconer T; Janssen Research and Development, Titusville, NJ, USA.
  • Fernandez-Bertolin S; Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.
  • Gao W; Department of Veterans Affairs, Salt Lake City, UT, USA.
  • Golozar A; University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Hardin J; Department of Biomedical Informatics, Columbia University, New York, NY, USA.
  • Hripcsak G; Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.
  • Huser V; Health Economics and Outcomes Research, AbbVie, North Chicago, IL, USA.
  • Jeon H; Pharmacoepidemiology, Regeneron, NY, USA.
  • Jing Y; Department of Epidemiology, Johns Hopkins School of Public, Baltimore, MD, USA.
  • Jung CY; Janssen Research and Development, Titusville, NJ, USA.
  • Kaas-Hansen BS; Department of Biomedical Informatics, Columbia University, New York, NY, USA.
  • Kaduk D; New York-Presbyterian Hospital, New York, NY, USA.
  • Kent S; National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
  • Kim Y; Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.
  • Kolovos S; Health Economics and Outcomes Research, AbbVie, North Chicago, IL, USA.
  • Lane JCE; Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Daegu Catholic University Medical Center, Daegu, Korea.
  • Lee H; Clinical Pharmacology Unit, Zealand University Hospital, Køge, Denmark.
  • Lynch KE; NNF Centre for Protein Research, University of Copenhagen, København, Denmark.
  • Makadia R; Odysseus Data Services, Inc., Cambridge, MA, USA.
  • Matheny ME; Department of Pediatrics № 2, V. N. Karazin Kharkiv National University, Kharkiv, Ukraine.
  • Mehta PP; Science Policy and Research, National Institute for Health and Care Excellence, London, UK.
  • Morales DR; Department of Orthopaedic Surgery, College of Medicine, Hanyang University, Seoul, Korea.
  • Natarajan K; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.
  • Nyberg F; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.
  • Ostropolets A; Bigdata Department, Health Insurance Review & Assessment Service, Wonju, Korea.
  • Park RW; Department of Veterans Affairs, Salt Lake City, UT, USA.
  • Park J; University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Posada JD; Janssen Research and Development, Titusville, NJ, USA.
  • Prats-Uribe A; GRECC, Tennessee Valley Healthcare System VA, Nashville, TN, USA.
  • Rao G; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Reich C; College of Medicine-Tucson, University of Arizona, Tucson, AZ, USA.
Nat Commun ; 11(1): 5009, 2020 10 06.
Article em En | MEDLINE | ID: mdl-33024121
ABSTRACT
Comorbid conditions appear to be common among individuals hospitalised with coronavirus disease 2019 (COVID-19) but estimates of prevalence vary and little is known about the prior medication use of patients. Here, we describe the characteristics of adults hospitalised with COVID-19 and compare them with influenza patients. We include 34,128 (US 8362, South Korea 7341, Spain 18,425) COVID-19 patients, summarising between 4811 and 11,643 unique aggregate characteristics. COVID-19 patients have been majority male in the US and Spain, but predominantly female in South Korea. Age profiles vary across data sources. Compared to 84,585 individuals hospitalised with influenza in 2014-19, COVID-19 patients have more typically been male, younger, and with fewer comorbidities and lower medication use. While protecting groups vulnerable to influenza is likely a useful starting point in the response to COVID-19, strategies will likely need to be broadened to reflect the particular characteristics of individuals being hospitalised with COVID-19.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Influenza Humana / Pandemias / Hospitalização Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / Asia / Europa Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Espanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Influenza Humana / Pandemias / Hospitalização Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / Asia / Europa Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Espanha