Increase in visceral adipose tissue in a woman living with HIV after introduction of integrase strand transfer inhibitor.
Int J STD AIDS
; 31(14): 1407-1410, 2020 12.
Article
em En
| MEDLINE
| ID: mdl-33081650
ABSTRACT
Integrase strand transfer inhibitors (INSTIs) are a class of antiretroviral drugs with high virologic efficacy and excellent tolerability. Recent evidence showed a possible link of dolutegravir-based regimens with weight gain, and a relationship between raltegravir use and changes in adipose tissue density and metabolic abnormalities, with an increased cardiovascular risk, has been suggested. We describe a case where dolutegravir monotherapy led to a decrease in adipose tissue density.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxazinas
/
Piperazinas
/
Piridonas
/
Composição Corporal
/
Infecções por HIV
/
Inibidores de Integrase de HIV
/
Compostos Heterocíclicos com 3 Anéis
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Int J STD AIDS
Assunto da revista:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Itália