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The IL1-IL1RAP axis plays an important role in the inflammatory leukemic niche that favors acute myeloid leukemia proliferation over normal hematopoiesis
De Boer, Bauke; Sheveleva, Sofia; Apelt, Katja; Vellenga, Edo; Mulder, André B; Huls, Gerwin; Jacob Schuringa, Jan.
Afiliação
  • De Boer B; Department of Experimental Hematology, Cancer Research Centre Groningen, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; Present address: The Finsen Laboratory, Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.
  • Sheveleva S; Department of Experimental Hematology, Cancer Research Centre Groningen, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Apelt K; Department of Experimental Hematology, Cancer Research Centre Groningen, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Vellenga E; Department of Experimental Hematology, Cancer Research Centre Groningen, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Mulder AB; Department of Laboratory Medicine, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands.
  • Huls G; Department of Experimental Hematology, Cancer Research Centre Groningen, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Jacob Schuringa J; Department of Experimental Hematology, Cancer Research Centre Groningen, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. j.j.schuringa@umcg.nl.
Haematologica ; 106(12): 3067-3078, 2021 12 01.
Article em En | MEDLINE | ID: mdl-33121233
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Interleucina-1beta / Proteína Acessória do Receptor de Interleucina-1 / Nicho de Células-Tronco Limite: Humans Idioma: En Revista: Haematologica Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Interleucina-1beta / Proteína Acessória do Receptor de Interleucina-1 / Nicho de Células-Tronco Limite: Humans Idioma: En Revista: Haematologica Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca