Inhibition of mTOR decreases insoluble proteins burden by reducing translation in C. elegans.

Yee, Zhuangli; Lim, Shaun Hsien Yang; Ng, Li Fang; Gruber, Jan

Yee, Zhuangli; Lim, Shaun Hsien Yang; Ng, Li Fang; Gruber, Jan.

Afiliação

Yee Z; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Lim SHY; Aging Research Laboratory, Science Division, Yale-NUS College, Singapore, Singapore.
Ng LF; Aging Research Laboratory, Science Division, Yale-NUS College, Singapore, Singapore.
Gruber J; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. jangruber467@gmail.com.

Biogerontology ; 22(1): 101-118, 2021 02.

Article em En | MEDLINE | ID: mdl-33159806

Assuntos

Proteínas de Caenorhabditis elegans; Caenorhabditis elegans; Animais; Proteínas de Caenorhabditis elegans/genética; Resposta ao Choque Térmico; Longevidade; Serina-Treonina Quinases TOR

Palavras-chave

Aging; C. elegans; Heat shock protein; Insoluble proteins; Proteostasis; mTOR

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Caenorhabditis elegans / Proteínas de Caenorhabditis elegans Limite: Animals Idioma: En Revista: Biogerontology Assunto da revista: GERIATRIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Singapura

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