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Serological methods for detection of infection with shrew-borne hantaviruses: Thottapalayam, Seewis, Altai, and Asama viruses.
Wei, Zhouoxing; Shimizu, Kenta; Nishigami, Kumpei; Tsuda, Yoshimi; Sarathukumara, Yomani; Muthusinghe, Devinda S; Gamage, Chandika D; Granathne, Lishanta; Lokupathirage, Sithumini M W; Nanayakkara, Nishanta; Arikawa, Jiro; Kikuchi, Fuka; Tanaka-Taya, Keiko; Suzuki, Motoi; Morikawa, Shigeru; Arai, Satoru; Yoshimatsu, Kumiko.
Afiliação
  • Wei Z; Graduate School of Infectious Diseases, Hokkaido University, Sapporo, 060-8638, Japan.
  • Shimizu K; Department of Microbiology and Immunology, Faculty of Medicine, Hokkaido University, Sapporo, 060-8638, Japan.
  • Nishigami K; Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Tsuda Y; Department of Microbiology and Immunology, Faculty of Medicine, Hokkaido University, Sapporo, 060-8638, Japan.
  • Sarathukumara Y; Department of Microbiology and Immunology, Faculty of Medicine, Hokkaido University, Sapporo, 060-8638, Japan.
  • Muthusinghe DS; Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Gamage CD; Department of Microbiology, Faculty of Medicine, University of Peradeniya, Kandy, Sri Lanka.
  • Granathne L; Graduate School of Infectious Diseases, Hokkaido University, Sapporo, 060-8638, Japan.
  • Lokupathirage SMW; Department of Microbiology, Faculty of Medicine, University of Peradeniya, Kandy, Sri Lanka.
  • Nanayakkara N; Girandrukotte District Hospital, Renal Clinic, District Hospital, Girandurukotte, Sri Lanka.
  • Arikawa J; Graduate School of Infectious Diseases, Hokkaido University, Sapporo, 060-8638, Japan.
  • Kikuchi F; Nephrology and Transplantation Unit, Teaching Hospital Kandy, Kandy, Sri Lanka.
  • Tanaka-Taya K; Department of Microbiology and Immunology, Faculty of Medicine, Hokkaido University, Sapporo, 060-8638, Japan.
  • Suzuki M; Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Morikawa S; National Institute of Infectious Diseases, Tokyo, Japan.
  • Arai S; Research and Education Center for Prevention of Global Infectious Diseases of Animals, Tokyo University of Agriculture and Technology, Fuchu, Japan.
  • Yoshimatsu K; National Institute of Infectious Diseases, Tokyo, Japan.
Arch Virol ; 166(1): 275-280, 2021 Jan.
Article em En | MEDLINE | ID: mdl-33201342
ABSTRACT
The infectivity of shrew-borne hantaviruses to humans is still unclear because of the lack of a serodiagnosis method for these viruses. In this study, we prepared recombinant nucleocapsid (rN) proteins of Seewis orthohantavirus, Altai orthohantavirus (ALTV), Thottapalayam thottimvirus (TPMV), and Asama orthohantavirus. Using monospecific rabbit sera, no antigenic cross-reactivity was observed. In a serosurvey of 104 samples from renal patients and 271 samples from heathy controls from Sri Lanka, one patient serum and two healthy control sera reacted with rN proteins of ALTV and TPMV, respectively. The novel assays should be applied to investigate potential infectivity of shrew-borne hantaviruses to humans.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Musaranhos / Orthohantavírus / Infecções por Hantavirus Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Animals / Humans País/Região como assunto: Asia Idioma: En Revista: Arch Virol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Musaranhos / Orthohantavírus / Infecções por Hantavirus Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Animals / Humans País/Região como assunto: Asia Idioma: En Revista: Arch Virol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão