A Second-Generation Fungerp Analog, SCY-247, Shows Potent <i>In Vitro</i> Activity against Candida auris and Other Clinically Relevant Fungal Isolates.

Chu, Sherman; Long, Lisa; Sherif, Rania; McCormick, Thomas S; Borroto-Esoda, Katyna; Barat, Stephen; Ghannoum, Mahmoud A

A Second-Generation Fungerp Analog, SCY-247, Shows Potent In Vitro Activity against Candida auris and Other Clinically Relevant Fungal Isolates.

Chu, Sherman; Long, Lisa; Sherif, Rania; McCormick, Thomas S; Borroto-Esoda, Katyna; Barat, Stephen; Ghannoum, Mahmoud A.

Afiliação

Chu S; Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA.
Long L; College of Osteopathic Medicine of the Pacific-Northwest (COMP), Lebanon, Oregon, USA.
Sherif R; Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA.
McCormick TS; Center for Medical Mycology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Borroto-Esoda K; Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA.
Barat S; Center for Medical Mycology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Ghannoum MA; Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA.

Antimicrob Agents Chemother ; 65(3)2021 02 17.

Article em En | MEDLINE | ID: mdl-33317999

Assuntos

Antifúngicos; Candida; Antifúngicos/farmacologia; Farmacorresistência Fúngica; Glicosídeos; Testes de Sensibilidade Microbiana

Palavras-chave

Ibrexafungerp; candidiasis; fungerps; triterpenoid class; ß-(1,3)-d-glucan

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Candida / Antifúngicos Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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