Of "Cotton Balls" and "Owl's eyes".
Malays J Pathol
; 42(3): 487-490, 2020 Dec.
Article
em En
| MEDLINE
| ID: mdl-33361734
ABSTRACT
Report of a 3-month old girl child who died due to multi-systemic infection of cytomegalovirus (CMV) involving the lungs, liver and kidneys along with pneumocystis jiroveci pneumonia (PJP). The mother of the child tested positive for CMV IgG and HIV with a very low CD4 count (160/ µl). Co-infection of cytomegalovirus and pneumocystis jiroveci always occurs in the setting of immunocompromise. Congenital CMV infection is transmitted through the placenta, especially during the first trimester and causes severe multi-systemic disease whereas perinatal infection is acquired during childbirth/ breastfeeding where the babies have maternal protective antibodies leading to much milder or asymptomatic infection. PJP is more common in infancy and presents as hypoxic pneumonia. CMV causes cyto-nucleomegaly and classic "owl's eye" inclusions on histology while PJP presents with characteristic fluffy "cotton ball" alveolar exudates.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pneumonia por Pneumocystis
/
Hospedeiro Imunocomprometido
/
Infecções por Citomegalovirus
Limite:
Female
/
Humans
/
Infant
Idioma:
En
Revista:
Malays J Pathol
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Índia