Bottom-up de novo design of functional proteins with complex structural features.

Yang, Che; Sesterhenn, Fabian; Bonet, Jaume; van Aalen, Eva A; Scheller, Leo; Abriata, Luciano A; Cramer, Johannes T; Wen, Xiaolin; Rosset, Stéphane; Georgeon, Sandrine; Jardetzky, Theodore; Krey, Thomas; Fussenegger, Martin; Merkx, Maarten; Correia, Bruno E

Yang, Che; Sesterhenn, Fabian; Bonet, Jaume; van Aalen, Eva A; Scheller, Leo; Abriata, Luciano A; Cramer, Johannes T; Wen, Xiaolin; Rosset, Stéphane; Georgeon, Sandrine; Jardetzky, Theodore; Krey, Thomas; Fussenegger, Martin; Merkx, Maarten; Correia, Bruno E.

Afiliação

Yang C; Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Sesterhenn F; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Bonet J; Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
van Aalen EA; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Scheller L; Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Abriata LA; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Cramer JT; Laboratory of Chemical Biology and Institute for Complex Molecular Systems, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.
Wen X; Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Rosset S; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Georgeon S; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Jardetzky T; Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Krey T; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Fussenegger M; Institute of Virology, Hannover Medical School, Hannover, Germany.
Merkx M; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
Correia BE; Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

Nat Chem Biol ; 17(4): 492-500, 2021 04.

Article em En | MEDLINE | ID: mdl-33398169

Assuntos

Engenharia de Proteínas/métodos; Motivos de Aminoácidos/genética; Sítios de Ligação/genética; Catálise; Ligantes; Modelos Moleculares; Ligação Proteica/genética; Dobramento de Proteína; Proteínas/química

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Engenharia de Proteínas Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça

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