Post-translational control of the long and winding road to cholesterol.

Sharpe, Laura J; Coates, Hudson W; Brown, Andrew J

Sharpe, Laura J; Coates, Hudson W; Brown, Andrew J.

Afiliação

Sharpe LJ; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
Coates HW; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
Brown AJ; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia. Electronic address: aj.brown@unsw.edu.au.

J Biol Chem ; 295(51): 17549-17559, 2020 12 18.

Article em En | MEDLINE | ID: mdl-33453997

Assuntos

Colesterol/biossíntese; Processamento de Proteína Pós-Traducional/genética; Colesterol/química; Humanos; Hidroximetilglutaril-CoA Redutases/metabolismo; Oxirredutases atuantes sobre Doadores de Grupo CH-CH/metabolismo; Complexo de Endopeptidases do Proteassoma/metabolismo; Esqualeno Mono-Oxigenase/metabolismo; Ubiquitina/metabolismo; Ubiquitina-Proteína Ligases/metabolismo

Palavras-chave

E3 ubiquitin ligase; HMGCR; SM; acetylation; cholesterol; cholesterol metabolism; cholesterol regulation; cholesterol synthesis; phosphorylation; post-translational modification; post-translational modification (PTM); post-translational regulation; proteasome; protein degradation; ubiquitin ligase; ubiquitination; ubiquitylation (ubiquitination)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Colesterol Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália

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