The Role of Cathepsin B in the Degradation of Aß and in the Production of Aß Peptides Starting With Ala2 in Cultured Astrocytes.

Oberstein, Timo Jan; Utz, Janine; Spitzer, Philipp; Klafki, Hans Wolfgang; Wiltfang, Jens; Lewczuk, Piotr; Kornhuber, Johannes; Maler, Juan Manuel

Oberstein, Timo Jan; Utz, Janine; Spitzer, Philipp; Klafki, Hans Wolfgang; Wiltfang, Jens; Lewczuk, Piotr; Kornhuber, Johannes; Maler, Juan Manuel.

Afiliação

Oberstein TJ; Department of Psychiatry and Psychotherapy, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany.
Utz J; Department of Psychiatry and Psychotherapy, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany.
Spitzer P; Department of Psychiatry and Psychotherapy, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany.
Klafki HW; Department of Psychiatry and Psychotherapy, University Medical Center, Georg-August-University, Göttingen, Germany.
Wiltfang J; Department of Psychiatry and Psychotherapy, University Medical Center, Georg-August-University, Göttingen, Germany.
Lewczuk P; German Center for Neurodegenerative Diseases, Göttingen, Germany.
Kornhuber J; Neurosciences and Signaling Group, Department of Medical Sciences, Institute of Biomedicine, University of Aveiro, Aveiro, Portugal.
Maler JM; Department of Psychiatry and Psychotherapy, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany.

Front Mol Neurosci ; 13: 615740, 2020.

Article em En | MEDLINE | ID: mdl-33510618

Palavras-chave

Alzheimer's disease; N-terminus; amyloid beta; astrocytes; cathepsin B; lysosomal

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Mol Neurosci Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha

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