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Design, synthesis, molecular docking, in silico ADMET profile and anticancer evaluations of sulfonamide endowed with hydrazone-coupled derivatives as VEGFR-2 inhibitors.
Sayed, Asmaa M; Taher, Fatma A; Abdel-Samad, Mohammad R K; El-Gaby, Mohamed S A; El-Adl, Khaled; Saleh, Nashwa M.
Afiliação
  • Sayed AM; Department of Chemistry, Faculty of Science, Al-Azhar University (Girls Branch), PO Box 11754, Cairo, Egypt.
  • Taher FA; Department of Chemistry, Faculty of Science, Al-Azhar University (Girls Branch), PO Box 11754, Cairo, Egypt; Al-Azhar Technology Incubator (ATI), Al-Azhar University, Cairo, Egypt.
  • Abdel-Samad MRK; Department of Zoology and Entomology, Faculty of Science, Al-Azhar University, Cairo, Egypt; Al-Azhar Technology Incubator (ATI), Al-Azhar University, Cairo, Egypt.
  • El-Gaby MSA; Department of Chemistry, Faculty of Science, Al-Azhar University at Assiut, Assiut 71524, Egypt.
  • El-Adl K; Pharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City 11884, Cairo, Egypt; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development, Cairo, Egypt. Electronic address: eladlkhaled74@
  • Saleh NM; Department of Chemistry, Faculty of Science, Al-Azhar University (Girls Branch), PO Box 11754, Cairo, Egypt. Electronic address: drnashwamostafa@azhar.edu.eg.
Bioorg Chem ; 108: 104669, 2021 03.
Article em En | MEDLINE | ID: mdl-33515863
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Desenho de Fármacos / Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Inibidores de Proteínas Quinases / Simulação de Acoplamento Molecular / Hidrazonas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Egito
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Desenho de Fármacos / Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Inibidores de Proteínas Quinases / Simulação de Acoplamento Molecular / Hidrazonas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Egito