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Known Drugs Identified by Structure-Based Virtual Screening Are Able to Bind Sigma-1 Receptor and Increase Growth of Huntington Disease Patient-Derived Cells.
Battista, Theo; Pascarella, Gianmarco; Staid, David Sasah; Colotti, Gianni; Rosati, Jessica; Fiorillo, Annarita; Casamassa, Alessia; Vescovi, Angelo Luigi; Giabbai, Barbara; Semrau, Marta Stefania; Fanelli, Sergio; Storici, Paola; Squitieri, Ferdinando; Morea, Veronica; Ilari, Andrea.
Afiliação
  • Battista T; Institute of Molecular Biology and Pathology, National Research Council of Italy, 00185 Rome, Italy.
  • Pascarella G; Department of Biochemical Sciences "A. Rossi Fanelli", "Sapienza" University, 00185 Rome, Italy.
  • Staid DS; Institute of Molecular Biology and Pathology, National Research Council of Italy, 00185 Rome, Italy.
  • Colotti G; Department of Biochemical Sciences "A. Rossi Fanelli", "Sapienza" University, 00185 Rome, Italy.
  • Rosati J; Institute of Molecular Biology and Pathology, National Research Council of Italy, 00185 Rome, Italy.
  • Fiorillo A; Department of Biochemical Sciences "A. Rossi Fanelli", "Sapienza" University, 00185 Rome, Italy.
  • Casamassa A; Institute of Molecular Biology and Pathology, National Research Council of Italy, 00185 Rome, Italy.
  • Vescovi AL; Cellular Reprogramming Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy.
  • Giabbai B; Department of Biochemical Sciences "A. Rossi Fanelli", "Sapienza" University, 00185 Rome, Italy.
  • Semrau MS; Cellular Reprogramming Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy.
  • Fanelli S; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.
  • Storici P; Cellular Reprogramming Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy.
  • Squitieri F; Protein Facility, Structural Biology Lab, Elettra Sincrotrone Trieste, 34149 Basovizza, Italy.
  • Morea V; Protein Facility, Structural Biology Lab, Elettra Sincrotrone Trieste, 34149 Basovizza, Italy.
  • Ilari A; Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, 38123 Trento, Italy.
Int J Mol Sci ; 22(3)2021 Jan 28.
Article em En | MEDLINE | ID: mdl-33525510
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Receptores sigma / Doença de Huntington / Fibroblastos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Adult / Humans / Male / Middle aged Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Receptores sigma / Doença de Huntington / Fibroblastos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Adult / Humans / Male / Middle aged Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália