Contribution of pulmonary diseases to COVID-19 mortality in a diverse urban community of New York.
Chron Respir Dis
; 18: 1479973120986806, 2021.
Article
em En
| MEDLINE
| ID: mdl-33550849
ABSTRACT
We examined the relative contribution of pulmonary diseases (chronic obstructive pulmonary disease, asthma and sleep apnea) to mortality risks associated with Coronavirus Disease (COVID-19) independent of other medical conditions, health risks, and sociodemographic factors. Data were derived from a large US-based case series of patients with COVID-19, captured from a quaternary academic health network covering New York City and Long Island. From March 2 to May 24, 2020, 11,512 patients who were hospitalized were tested for COVID-19, with 4,446 (38.62%) receiving a positive diagnosis for COVID-19. Among those who tested positive, 959 (21.57%) died of COVID-19-related complications at the hospital. Multivariate-adjusted Cox proportional hazards modeling showed mortality risks were strongly associated with greater age (HR = 1.05; 95% CI 1.04-1.05), ethnic minority (Asians, Non-Hispanic blacks, and Hispanics) (HR = 1.26; 95% CI, 1.10-1.44), low household income (HR = 1.29; 95% CI 1.11, 1.49), and male sex (HR = 0.85; 95% CI 0.74, 0.97). Higher mortality risks were also associated with a history of COPD (HR = 1.27; 95% CI 1.02-1.58), obesity (HR = 1.19; 95% CI 1.04-1.37), and peripheral artery disease (HR = 1.33; 95% CI 1.05-1.69). Findings indicate patients with COPD had the highest odds of COVID-19 mortality compared with patients with pre-existing metabolic conditions, such as obesity, diabetes and hypertension. Sociodemographic factors including increased age, male sex, low household income, ethnic minority status were also independently associated with greater mortality risks.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Síndromes da Apneia do Sono
/
Saúde da População Urbana
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Mortalidade Hospitalar
/
Doença Pulmonar Obstrutiva Crônica
/
COVID-19
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Chron Respir Dis
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos